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Phytoextracts and Their Derivatives Affecting Neurotransmission Relevant to Alzheimer’s Disease
Published in Akula Ramakrishna, Victoria V. Roshchina, Neurotransmitters in Plants, 2018
The ethyl acetate extract of whole plants of Agrimonia pilosa (Family: Rosaceae) showed significant AChE inhibitory activity due to presence of quercetin [Figure 21.3 (xxxv)]. Inhibitory activity of quercetin is due to the presence of a catechol moiety on ring B, which facilitates quercetin binding to AChE (Natarajan et al., 2009).
Catalog of Herbs
Published in James A. Duke, Handbook of Medicinal Herbs, 2018
Said to alleviate condylomata, sclerosis of the spleen and liver, tumors of the internal organs, mesenteric region, scrotum, sinews, and stomach, as well as corns and warts, and cancer of the breast, face, mouth, and stomach.4 Reported to be astringent, cardiotonic, coagulant, depurative, diuretic, emmenagogue, litholytic, sedative, tonic, vermifuge, and vulnerary; agrimony is a folk remedy for asthma, bronchitis, dermatitis, enterorrhagia, enuresis, gastrorrhagia, hematuria, hepatosis, metrorrhagia, neuralgia, neuritis, pharyngitis, rheumatism, tuberculosis, and warts.32,33 Astringent, the herb tea is useful for internal bleeding, and/or looseness of the bowels. Has a great reputation for curing jaundice and other liver ailments. Also recommended for snakebite. Considered useful in gout, skin eruptions, pharyngitis, diseases of the blood, blotches, pimples, etc. Febrifugal and vermifugal; used for tapeworm, e.g., by the Zulu.3 Sotho use as vermifuge with Artemisia afra; the leaf is used for colds. Plant is gargled for inflammation of throat and mouth. Mixed with fat, it is used as a poultice to draw out indolent ulcers.47
Integrative hyperthermia treatments for different types of cancer
Published in Clifford L. K. Pang, Kaiman Lee, Hyperthermia in Oncology, 2015
Clifford L. K. Pang, Kaiman Lee
Medications: The proposed prescriptions were as follows: Atractylodes macrocephala Koidz 30 g, Poria Cocos 30 g, Radix glycyrrhizae Preparate 6 g, Alisma orientalis 30 g, Ramulus cinnamomi 6 g, Perilla seed 15 g, Prunella vulgaris 15 g, cowherb seed 30 g, Hedyotis diffusa Willd 30 g, Scutellaria barbata 15g, Agrimonia pilosa Ledeb 30 g, Lophatherum gracile Brongn 10 g, Juncus effusus L. 10 g, Radix rehmanniae 15 g, and Mentha haplocalyx Briq 6 g, one dose a day and decocted with water for oral intake.
Agrimoniin inhibits the activity of CYP1A2, 2D6, and 3A4 in human liver microsomes
Published in Xenobiotica, 2021
Yanqing Zhou, Qian Xian, Haimin Wei, Jin Zhou, Shengjian Li, Junwei Yang, Xuedong Zhou, Yamei Li
Agrimonia pilosa Ledeb. is traditional folk medicine that has been widely used as haemostatic, antiparasitic, and antidiarrheal agents. Agrimoniin is a major constituent of Agrimonia pilosa Ledeb. and it also existed in some commonly consumed food, such as strawberry and raspberry (Grochowski et al. 2017). The pharmacological properties of agrimoniin have also been widely reported. For example, agrimoniin showed an antitumor effect on fibrosarcoma and enhance immune response (Miyamoto et al. 1987). Herbal medicine is one of the most common treatment methods in paediatrics, which plays a crucial role in the healthcare system and has been used as alternative medicine worldwide. Herbal medicines are complex mixtures, and these complex mixtures may interact with each other, which makes it attract special attention and become largely different from western therapies (Ge 2019). Cytochrome P450 (CYP450) enzymes are key factors during these potential interactions.
Variability, toxicity, and antioxidant activity of Eupatorium cannabinum (hemp agrimony) essential oils
Published in Pharmaceutical Biology, 2016
Asta Judzentiene, Rasa Garjonyte, Jurga Budiene
Eupatorium cannabinum is a medicinal and aromatic herb with antibacterial, immunological, cytostatic, anti-inflammatory, fungicidal, etc. properties. In Lithuanian folk medicine, the plant has been used as a remedy for treatment of liver diseases and against diarrhea (Lekavicius, 1980). Currently hemp agrimony is used as a component for some homeopathic preparations.
Effects of Bushen Yiyuan recipe on testosterone synthesis in Leydig cells of rats with exercise-induced low serum testosterone levels
Published in Pharmaceutical Biology, 2022
Yirong Wang, Xiyang Peng, Zhihong Zhou, Changfa Tang, Wenfeng Liu
Bushen Yiyuan recipe (BYR) is an effective prescription of traditional Chinese medicine in clinical application, composed of more than 10 kinds of extracts, including ginsenoside from Ginseng radix et rhizome (the dried root and rhizome of Panax ginseng C. A. Meyer [Araliaceae]), icariin from Epimedii folium (the dried leaves of Epimedium brevicornu Maxim. [Berberidaceae]), Lycium polysaccharide from Lycii fructus (the dried and mature fruits of Lycium barbarum Linn. [Solanaceae]), aqueous extracts of Ligustri lucidi fructus (the dried and mature fruits of Ligustrum lucidum Ait. [Oleaceae]), aqueous extracts of Eucommiae cortex (the dried bark of Eucommia ulmoides Oliver [Eucommiaceae]), aqueous extracts of Astragali radix (the dried root of Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao [Leguminosae]), aqueous extracts of Agrimoniae herba (the dried overground part of Agrimonia pilosa Ledeb. [Rosaceae]), aqueous extracts of Dashenjincao (the dried whole plant of Phlegmariurus carinatus (Desv.) Ching [Huperziaceae]), aqueous extracts of Selaginellae herba (the dried whole plant of Selaginella tamariscina (Beauv.) Spring [Selagioellaceae]), aqueous extracts of Ajugae herba (the dried whole plant of Ajuga decumbens Thunb. [Lamiaceae]) (Liu et al. 2018; Wang et al. 2016). Ginsenoside, icariin, Lycium polysaccharide are the main ingredients of BYR. Animal experiments show that this recipe can enhance the aerobic and anaerobic endurance of swimming mice, and has the effects of anti-free radical damage, improving cell energy metabolism and improving the cellular immune function (Zhou et al. 2000, 2001). The clinical research of sports medicine also shows that BYR can keep the blood testosterone concentration relatively stable, reduce the blood cortisol and increase the haemoglobin (Hb) level during the exercise training of male rowers, to enhance the effect of physical fitness of athletes (He et al. 2004). Besides, it can relieve the related symptoms of sports fatigue of rowers, such as mental fatigue, limb weakness and short sense of breath during exercise (He et al. 2004). However, the effect of BYR on testicular interstitial fibrosis and its molecular mechanism are still unclear.