Explore chapters and articles related to this topic
The gastrointestinal system
Published in C. Simon Herrington, Muir's Textbook of Pathology, 2020
Sharon J. White, Francis A. Carey
Fibrous overgrowth of the oral mucosa is very common and frequently presents as a fibroepithelial polyp secondary to chronic trauma. An epulis is a localized swelling on the gingiva. A fibrous epulis typically occurs as a reaction to chronic irritation, e.g. from dental calculus (calcified plaque) or the rough margin of a carious cavity or filling. It consists of a mass of cellular fibrous tissue often with metaplastic bone formation. Pyogenic granulomas comprise a mass of granulation tissue, often ulcerated, and are found at any intraoral site, but most often form on the gingiva as a vascular epulis or, in pregnancy, as a pregnancy epulis. Giant cell epulis (peripheral giant cell granuloma) is a distinct lesion consisting of numerous multinucleated giant cells in a vascular stroma. It is a superficial lesion with minimal bone involvement. However, intraosseous lesions, such as central giant cell granuloma or lesions of hyperparathyroidism, may mimic a giant cell epulis clinically and histologically if they extend to involve the gingival soft tissues; thus, radiological and biochemical investigations are warranted in such cases.
Odontogenic Tumors
Published in Dongyou Liu, Tumors and Cancers, 2017
Odontogenic allied lesions (or bone-related lesions) encompass psammomatoid ossifying fibroma, trabecular ossifying fibroma, fibrous dysplasia, cemento-osseous dysplasia, central giant cell granuloma, cherubism, aneurysmal bone cyst, simple bone cyst, and melanotic neuroectodermal tumor of infancy [4].
Oral health status of pregnant women in Ilorin, Nigeria
Published in Journal of Obstetrics and Gynaecology, 2018
Kikelomo T. Adesina, Moninuola A. Ernest, Abiola O. Tobin, Salamat A. Isiaka-Lawal, Moshood F. Adeyemi, Adebunmi O. Olarinoye, Grace G. Ezeoke
The low prevalence of pregnancy epulis in this study was comparable to findings at the oral examination among pregnant women in Raichur India, and in Accra, Ghana (Annan and Nuamah 2005; Gupta and Acharya 2016). Pregnancy epulis, also known as pyogenic granuloma, results from the interplay between the hormonal effects, gingival vasculature and a poor oral hygiene in pregnancy. This causes a chronic gingivitis that is commonly observed in the third trimester and resolves spontaneously at 1–4 weeks’ postpartum. (Rabinerson et al. 2002; Saravanum et al. 2012). Epulis-like lesions outside a pregnancy are peripheral giant cell granuloma, a central giant cell granuloma and fibroma (Agrawal 2015).
A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws
Published in Acta Odontologica Scandinavica, 2021
Noura A. Alsufyani, Reem M. Aldosary, Rasha S. Alrasheed, Rand F. Alsaif
Central giant cell granuloma (CGCG) is a benign osseous lesion of the jaws. The exact aetiology of this lesion is still controversial, but the literature suggests three theories [1,2]. The first proposes a reactive origin to a local irritant; the second suggests that it is a developmental anomaly, and the third implicates a neoplastic aetiology [2]. CGCG accounts for 7% of all benign jaw tumours [3]. Histopathological examination reveals giant cell proliferation, numerous spindle-shaped mesenchymal cells, and erythrocyte extravasation in a fibrous stroma [4,5]. It is normally a slowly growing lesion, although an aggressive behaviour is not uncommon [3].
An expansive aneurysmal bone cyst of the maxillary sinus in an 8 year old child: Case report and review of literature
Published in Acta Oto-Laryngologica Case Reports, 2020
Milan Urík, Ivo Šlapák, Michaela Máchalová, Jana Jančíková, Soňa Šikolová, Denisa Pavlovská, Petr Jabandžiev, Marta Ježová
An ABC may be primary or arise secondarily in other benign or malignant bone tumors. The most frequent lesions are, in that case, the ossifying fibroma, the central giant cell granuloma and the fibrous dysplasia located in jaw bones specially in facial sinuses. Some forms of ABC are large and aggressive with potential sequelae and thus, of a tumoral nature [14] as in our case.