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ExperimentaL Oral Medicine
Published in Samuel Dreizen, Barnet M. Levy, Handbook of Experimental Stomatology, 2020
Samuel Dreizen, Barnet M. Levy
Epithelial-lined cysts of the jaws fall into two main classes. The first category is derived from epithelial cells that have completed their biologic function in tooth formation and is usually associated with inflammation. They are lined by nonkeratinizing epithelium with discontinuities and various signs of degeneration. The second group is derived from epithelium that has not contributed to normal tooth structure. Such cysts are usually associated with an active keratinizing epithelium and are free of inflammatory cell infiltrates. Soskolne et al.69 described a method for the experimental production of keratinizing cysts within rat mandibles by implantation of autogenous gingival epithelial grafts. In this study, 30 male albino rats, 140 to 185 g in weight, were anesthetized with pentobarbital sodium. A cavity was drilled into the exposed buccal surface of the mandible opposite the distal root of the first molar after reflecting the covering gingiva. The cavity was syringed with saline and plugged with a cotton pellet to control bleeding. The buccal aspect of the interdental papilla between the upper teeth was swabbed with 70% ethanol, washed with saline, and rinsed in 1% penicillin solution. Removal of the cotton pellet from the holes prepared in the mandible was followed by insertion of the incised papilla. Overlying tissues were sutured in place. The animals were sacrificed and the sites examined histologically after 0 to 45 days.
Cysts and Tumours of the Bony Facial Skeleton
Published in John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford, Head & Neck Surgery Plastic Surgery, 2018
Julia A. Woolgar, Gillian L. Hall
A simple definition of a cyst is ‘a cavity, generally lined by epithelium, filled with fluid or semi solid contents but not formed by the accumulation of pus’. As outlined above and summarized in Table 25.1, cysts of the jaws and bony facial skeleton arise from several types of epithelial residues. These residues probably exist within the jaws and covering alveolar/gingival mucoperiosteum in all individuals but the factors which lead to cyst formation are poorly understood.
Cysts of the jaws, face and neck
Published in John Dudley Langdon, Mohan Francis Patel, Robert Andrew Ord, Peter Brennan, Operative Oral and Maxillofacial Surgery, 2017
Dentigerous cysts of the jaws develop in association with impacted teeth, most commonly mandibular third molars. Maxillary third molars, maxillary canines and mandibular second premolars are also observed to be associated with dentigerous cysts. They may also occur in association with supernumerary teeth and odontomas; however, they are only rarely associated with primary teeth.1, 2 Although dentigerous cysts occur over a wide age range, they are most commonly seen in patients between the ages of 10 and 30 years. Many dentigerous cysts are small asymptomatic lesions that are discovered serendipitously on routine radiographs, although some may enlarge to considerable size thereby causing bony expansion.
Ameloblastoma: clinical presentation, multidisciplinary management and outcome
Published in Case Reports in Plastic Surgery and Hand Surgery, 2021
Abelardo Medina, Ignacio Velasco Martinez, Benjamin McIntyre, Ravi Chandran
Ameloblastoma is a rare head and neck tumor with an estimated annual incidence of 0.5 per million population [1,2]. They constitute 1% of tumors and cysts involving the jaws and accounts for approximately 10% of the odontogenic tumors [3]. Ameloblastomas are originated from the epithelial lining of odontogenic cysts, enamel organ or dental lamina, stratified epithelium of oral cavity or displaced epithelial remnants [4,5]. They are primarily seen in adults during the third and fourth decade of life with no gender preference and more frequently located in the mandible (80%), especially in the angle and ascending ramus [6].