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Tumors of the Nervous System
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
The WHO has designated three pathologic divisions based on histologic appearance: WHO grade I: Myxopapillary ependymoma, a benign tumor occurring in the filum terminale. Although benign, myxopapillary ependymoma may seed the CSF.Subependymoma, a very benign relative of ependymoma, usually located in the fourth ventricle or spinal cord, which is often asymptomatic. Subependymomas do not spread to the leptomeninges.WHO grade II: cellular, papillary, and clear cell variants. These tumors typically arise from the ventricular surface (fourth ventricle is most common) or spinal cord parenchyma.WHO grade III: anaplastic ependymoma, a more malignant behaving tumor with a tendency for leptomeningeal spread and even extra-CNS metastases.
Central Nervous System
Published in Pat Price, Karol Sikora, Treatment of Cancer, 2020
Myxopapillary ependymoma is a variant most commonly found in the sacral region. It is of low grade (Grade 1) and may often be watched following resection even if removal is incomplete. The rare subependymoma is a very low-grade lesion that should be treated with surgery alone.
Central nervous system
Published in Pat Price, Karol Sikora, Treatment of Cancer, 2014
Anthony Chalmers, Allan James, Roy Rampling
Myxopapillary ependymoma is a variant most commonly found in the sacral region. It is of low grade (grade 1) and may often be watched, following resection even if removal is incomplete. The rare subependymoma is a very-low-grade lesion that should be treated with surgery alone.
Etiological factors of spontaneous primary intraventricular hemorrhage
Published in British Journal of Neurosurgery, 2020
Zhongzhong Jiang, Yong Peng, Mingming Zhang, Mengqiang Yu
Intracranial tumor hemorrhage is rare as being a cause of SIVH without parenchymal hemorrhage. There are only a small number of case reports, the locations of tumors related to intraventricular hemorrhage were mainly the ventricle and the base of the skull (anterior cranial fossa, middle cranial fossa, and posterior fossa).19–22 In our study, there was only one case of neoplastic intraventricular hemorrhage. A 20-year-old woman was admitted to hospital after having a headache for a month and vomiting several times. On admission, a CT scan showed a spontaneous intraventricular hemorrhage, then MRI and MRA examination of the head showed intraventricular occupation without vascular abnormalities. A resection was performed 6 days later, and the postoperative pathological examination showed subependymoma.
Survival of patients and risk factors for subependymoma: a population-based study
Published in Neurological Research, 2023
Gui-Jun Zhang, Xu Cheng, Cong Chen, Chao You
According to a literature review, we observed that available information on subependymoma was rare and mostly limited to case reports and small case series [9–12], with no detailed information performed on a large cohort. Accordingly, the Surveillance, Epidemiology, and End Results (SEER) database (http://seer.cancer.gov/) is the authoritative cancer statistics data in the United States, with a large sample size. In addition, samples from multiple populations make studies based on the SEER database of high clinical value. Thus, in the present study, in which we performed the largest-to-date SEER analysis of subependymoma, we aimed to evaluate and identify risk factors for this tumor.
Apoplexy of a collision tumour composed of subependymoma and cavernous-like malformation in the lateral ventricle: a case report
Published in British Journal of Neurosurgery, 2019
Motaz Alsereihi, Fatima Turkistani, Fahad Alghamdi, Saleh Baeesa
To our knowledge, there was no reported case in the literature of subependymoma associated with a vascular lesion before. We hypothesize that this association could be either due to the possible genetic linkage, or neoplastic transformation of adjacent glial tissue as a result of chronic stimulation by local growth factors like vascular endothelial growth factor.