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Congenital nevi
Published in Prem Puri, Newborn Surgery, 2017
Lee W. T. Alkureishi, Bruce S. Bauer
Although not usually congenital, spitz nevi are another commonly encountered pediatric skin lesion. They present as pink, raised, firm lesions that can occasionally be pigmented (Figure 86.8). At times, they may be confused with pyogenic granulomas because of their appearance and rapid growth at onset. Originally termed benign juvenile melanoma, these lesions display a bizarre pathology beneath the microscope and can be confused with malignancy if the pathologist is not provided with the history of the lesion and patient’s age. In fact, these lesions are benign, but do grow rapidly and tend to recur aggressively if not completely excised. Because of that, these lesions should be excised with a generous 3–4 mm border of normal tissue to decrease the chance of recurrence.
Challenging Melanocytic Neoplasms: Spitzoid Melanoma Vs. Spitz Nevus
Published in Sanjiv S. Agarwala, Vernon K. Sondak, Melanoma, 2008
Julide T. Celebi, Julide T. Celebi
Spitz nevi typically occur in children and adolescents, although they can occur in adults. By contrast, melanomas of all types, including Spitzoid melanoma, are rare in children and occur typically in adults. The Centers for Disease Control and Prevention estimated 475 new cases of melanoma in the United States in 2002 for persons aged 19 years or below and only 47 new cases in children aged below 10 years (7). Therefore, the diagnosis of Spitzoid melanoma in children is especially difficult, and accurate diagnosis is most challenging in this age group.
Cutaneous eyelid melanoma in an African American child
Published in Orbit, 2021
Jan P. Ulloa-Padilla, Armen Khararjian, Catherine J. Choi
These subtle differences in the pediatric population between benign lesions and melanoma are not limited to the clinical appearance, but also involve the histopathological analysis.5 Microscopic examination of melanoma most often shows the classic features of neoplasia with variable amount of pigmentation. However, a similar notable entity in the differential diagnosis is the Spitz nevus (SN).,4,5 SN may share multiple histological features with melanoma such as the presence of spindle cells, epithelioid cells with prominent nucleoli, possible pagetoid spread, lymphatic invasion and prominent vasculature.4 While a SN can often be differentiated from a CM based on clinical presentation, the possibility of an atypical SN complicates the diagnostic confidence.
Application of automatic statistical post-processing method for analysis of ultrasonic and digital dermatoscopy images
Published in Libyan Journal of Medicine, 2018
Indre Drulyte, Tomas Ruzgas, Renaldas Raisutis, Skaidra Valiukeviciene, Gintare Linkeviciute
The purposes of exploration of the lesion parameters of human tissue are to have a faster diagnosis, informative prediction of the illness, also to reduce the cost of possible treatment, and to save as much lives as it is feasible. The main task is to find the way which leads to accurate diagnostics. First signs of the dermatoscopy appeared in 1948 and a Spitz nevus was introduced as ‘melanoma of childhood’ due to the potentiality of the technologies and histopathologic features at that time [5]. In 1953, Arthur C. Allen, Helwig in 1954, and other researches continued their investigations from the classification of benign and malignant nevus perspective [6]. Later, in 1987, Pehamberger et al. presented a new diagnostic approach named as a ‘pattern analysis’ [7]. Pattern analysis was designated to detect and provide diagnostic accuracy for pigmented skin lesions diseases, such as melanoma and other skin damages [7].
Efficacy of the carbon dioxide fractional laser in the treatment of compound and dermal facial nevi using with dermatoscopic follow-up
Published in Journal of Dermatological Treatment, 2019
We performed a retrospective review of 330 patients with 684 compound and dermal facial nevi on the face between June 2013 and June 2017 that were treated by ablative CO2 fractional laser. Informed consent was obtained from all the patients. All lesions were pigmented, elevated, with brown or skin color, papular or nodular shape, and did not exceed 10 mm in diameter. For nevi localization, the face was segmented into five different areas: forehead, cheeks, chin, lips, and nose. Individuals with nevi such as congenital or acquired junctional melanocytic, Blue, or Spitz nevi and also with a personal or family history of melanoma, hypertrophic scarring, and/or keloid formation were excluded.