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Intense pulsed light
Published in Dimitris Rigopoulos, Alexander C. Katoulis, Hyperpigmentation, 2017
Owen Kramer, Benjamin C. Garden, Maria Tsoukas
A nevus spilus is usually acquired in early childhood and appears, most commonly on the trunk or extremity, as a tan or lentiginous lesion where many dark nevus-like lesions may emerge resulting in a spotted appearance; development of melanoma in these lesions is a rare but reported event.61 There have been a few reported studies of the use of IPL in the treatment of this relatively uncommon lesion; in 1999, Gold et al.46 reported a case where a patient with a nevus spilus experienced marked clearing after four sessions of IPL; this result was maintained for a 6-month follow-up.
A retrospective study of FQSRL and IPL in the treatment of Café-au-lait macule
Published in Journal of Dermatological Treatment, 2021
Tianshu Gu, Jinping Yuan, Yanping Zhang, Yuan-Hong Li, Yan Wu, Xing-Hua Gao, Hong-Duo Chen
The earliest successful clinical use of IPL was the treatment of photoaged skin in an Asian population (17). Its effect is primarily broad and gentle causing a gradual uniform response, as the targets of IPL were multiform. And IPL has been recommended for treatment of pigmented lesions. In a previous study of IPL for melanocytic lesions (CALM, ephelides, melasma, nevus spilus, epidermal nevus, nevus of Becker), four CALM cases all achieved >75% improvement (18). In the present study, 45% CALM patients achieved >50% improvement by three sessions of IPL, and 87.5% achieved >50% improvement by more than four sessions. More than four sessions of IPL produced better efficacy than less sessions. Although FQSRL presented more favorable responses than IPL, IPL could be an alternative choice with safer profile for some patients (especially darker skin).
Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea
Published in Journal of Cosmetic and Laser Therapy, 2019
Bo Young Kim, Hye-Rim Moon, Hwa Jung Ryu
In this study, we measured the melanin indices after the IPL and PDL treatments and reported statistically significant improvement of pigmentation in both treatments. IPL has been widely used to treat pigmentary disorders including melasma (21), solar lentigines and ephelides (22), poikiloderma of Civatte (23), and nevus spilus, café-au-lait macules, post-inflammatory hyperpigmentation, and Riehl’s melanosis (24), and all appear to respond reasonably well. With PDL, there have been studies on treating pigmentary disorders along with other treatments including triple combination cream (25) and 1927-nm fractional low-powered diode laser (26) but not of PDL alone. Melanocytes express vascular endothelial growth factor (VEGF) receptors 1 and 2 and neuropilin. Thus, VEGF and skin vascularization might play a role in pigmentation processes (27). In these cases, rosacea can be accompanied with pigmentary disorders such as melasmas, solar lentigines, and post-inflammatory hyperpigmentation. Compared with baseline, the erythema and melanin indices improved significantly after four treatments with both PDL and IPL, and there were no significant differences between treatments in either index. These results suggested that treatment with PDL only, not in combination with pigment-specific modalities, may improve lesions to address both the vascular and pigment components such as rosacea with melasma and melasma with telangiectasia.
Efficacy of 1064-nm Nd:YAG picosecond laser in lichen amyloidosis treatment: clinical and dermoscopic evaluation
Published in Journal of Cosmetic and Laser Therapy, 2021
Suparuj Lueangarun, Therdpong Tempark
Rather than using biophysical evaluation, our study evaluated the efficacies of 1,064 nm ps-Nd:YAG laser in the treatment of LA from clinical, patient satisfaction, itching score, and dermoscopic evaluation. To our knowledge, there has been no study of LA treated with 1,064 nm ps-Nd:YAG laser. Nonetheless, Picosecond lasers (ps-lasers) are used for treatment of various pigmented lesions, such as nevus of Ito, congenital nevus, nevus spilus, nevus of Ota, Hori’s macules, café-au-lait patches, lentigines, and Becker nevus, with promising results (14).