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The salivary glands
Published in Neeraj Sethi, R. James A. England, Neil de Zoysa, Head, Neck and Thyroid Surgery, 2020
Basal cell adenoma is characteristically encapsulated. It has an intact basement membrane, which differentiates it from pleomorphic adenoma. It can be difficult to distinguish from solid adenoid cystic carcinoma on biopsy [19].
Brooke–Spiegler Syndrome
Published in Dongyou Liu, Handbook of Tumor Syndromes, 2020
Basal cell adenoma of membranous type (which is histologically similar to dermal cylindroma) is a common benign tumor occurring in the salivary glands, and appears to have evolved from precursor lesions (either hyperplasia of reserve cells in intercalated ducts or proliferative lobular buds with prominent hyaline material, and microadenomatous foci adjacent to intercalated ducts or acini). Malignant transformation of a preexisting membranous basal cell adenoma leads to either low-grade or high-grade basal cell adenocarcinoma [31].
The role of frozen section biopsy for submandibular gland tumors
Published in Acta Oto-Laryngologica, 2021
Masahiro Suzuki, Yuta Nakaegawa, Tomotaka Kawase, Masakazu Ikeda, Shigeyuki Murono
Among the 42 patients who had undergone FNAC and FSB, 37, four and one were diagnosed as having benign, indeterminate and malignant tumors, respectively, by FNAC. Of the 37 benign cases, FNAC revealed suspected pleomorphic adenoma (PA) in 24 cases, and could not histologically identify 13 cases. The malignant case detected was suspected to be adenoid cystic carcinoma. Using FSB, 36, three and three cases were diagnosed as benign, indeterminate, and malignant, respectively. Of the 36 benign cases, FSB revealed suspected PA in 34 cases and suspected basal cell adenoma in one case, and could not histologically identify one case. Of the three malignant cases, FSB revealed suspected solitary fibrous tumor in one case, adenocarcinoma in one case, and adenoid cystic carcinoma in one case. The final histological diagnoses showed that 38 cases were benign and four were malignant. All 38 histologically benign cases were PA. The histological tumor types of the four malignant cases included three cases of adenoid cystic carcinoma and one case of carcinoma ex PA (Table 1).
Comparative outcomes of extracapsular dissection and superficial parotidectomy
Published in Acta Oto-Laryngologica, 2019
Kerem Ozturk, Arin Ozturk, Goksel Turhal, Isa Kaya, Serdar Akyildiz, Umit Uluoz
The tumour pathology was pleomorphic adenomas in 66 cases (48.5%), Warthin tumour in 63 cases (46.3%), basal cell adenoma in 4 cases (2.9%) and myoepithelioma in 3 cases (2.2%). Numbers of the different tumour pathologies of two groups were shown in Table 1. No malignancy was reported in the postoperative pathology specimens. Among SP patient group, 11 (14.1%) seroma/hematoma and 4 (5.1%) salivary fistula were observed. In patients with ECD, there were no early postoperative complications due to the surgery. In the SP group, three patients had recurrence (3.8%), 8 (10.2%) patients had early facial nerve paralysis (grade 2 and 3), and 11 (14.1%) patients had Frey Syndrome. All patients with facial nerve palsy showed complete recovery in the postoperative follow-up. All of the recurrent patients were diagnosed with pleomorphic adenoma and the mean follow-up time until recurrence was 22.3 months (range 18–27). In 58 patients undergoing ECD, no postoperative complication or early facial paralysis was observed. No recurrence was present in the ECD group. Rates of transient facial nerve palsy, Frey’s syndrome and seroma/hematoma formation were significantly higher in SP group. There was no statistically significant difference in tumour recurrence between two groups (p: .261). Summarised statistical data of postoperative complications of two groups were shown in Table 2.