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The reproductive system
Published in Laurie K. McCorry, Martin M. Zdanowicz, Cynthia Y. Gonnella, Essentials of Human Physiology and Pathophysiology for Pharmacy and Allied Health, 2019
Laurie K. McCorry, Martin M. Zdanowicz, Cynthia Y. Gonnella
Uterine prolapse is a condition that occurs when the muscle and ligaments that support the uterus stretch and weaken. As a result, the uterus can enter the vagina and even protrude externally. The condition is most likely to occur in women who had multiple vaginal deliveries. Mild prolapse may not require treatment and may be improved with specific exercises. More severe cases will likely require surgical correction.
Hysteropexy with single-incision vaginal support system associated with a modified culdoplasty for enterocele prevention
Published in Journal of Obstetrics and Gynaecology, 2020
Giuseppe Ettore, Gabriella Torrisi, Carla Ettore, Vincenzo Guardabasso
We performed a prospective clinical observational study on patients undergoing primary surgery for POP at the secondary referral Uro-Gynaecological Unit of the Women and Children's Department-ARNAS Garibaldi-Nesima from February 2016 to January 2017. The study has been approved by the local ethics committee. All of the patients with a symptomatic multi-compartment prolapse POP-Q stage ≥2 (according to the Pelvic Organ Prolapse Quantification (POP-Q) system) were eligible for the study. The patients were screened by the operating surgeon for uterine prolapse (apical prolapse, point C > –1), with vaginal anterior wall prolapse ≥stage 2 (point Ba>–1), according to the POP-Q system. There were no restrictions with regard to weight, parity and menopausal status. The exclusion criteria included: previous surgery, abnormal uterine bleeding, current pelvic organ cancer, severe rheumatic disease, connective tissue disorder and current systemic steroid treatment. The patients with associated pelvic disorders requiring surgical treatment, i.e. stress incontinence, cervix elongation and symptomatic posterior prolapse, were not included in the study. A standardised questionnaire regarding symptoms of prolapse, urinary or anal incontinence was administered. The pre-operative work-up included a physical examination according to the POP-Q system.
Surgical management of pelvic organ prolapse
Published in Climacteric, 2019
C. F. Maher, K. K. Baessler, M. D. Barber, C. Cheong, E. C. J. Consten, K. G. Cooper, X. Deffieux, V. Dietz, R. E. Gutman, J. J. van Iersel, C. W. Nager, V. W. Sung, R. de Tayrac
Upon completion of a surgical pathway, reflection on the pathway and the quality of the data that inform the recommendations is appropriate and important in identifying future research needs. The quality of the data that inform the obliterative, vault, and anterior compartment arms is relatively robust and consistent, indicating that a single further trial in these areas on the same topic is unlikely to significantly change the decision tree. However, the quality of data in the management of uterine prolapse including comparisons between hysterectomy and uterine preservation and options within each group require further evaluation. Uterine prolapse represents a very significant group of women presenting with vaginal prolapse, and well-conducted, large trials evaluating this topic are needed.
Climacteric women at work: What lurks behind poor occupational quality of life?
Published in Health Care for Women International, 2018
Tatjana Gazibara, Biljana Rancic, Sanja Radovanovic, Ilma Kurtagic, Selmina Nurkovic, Nikolina Kovacevic, Jelena Dotlic
In this study, uterine prolapse remained associated with poorer occupational QOL when this score was analyzed as continuous as well as binary value. Uterine prolapse is one of the most common gynecological conditions, resulting from adaptive changes of the pelvic floor throughout life and its frequency correlates with age (Mannella, Palla, Bellini, & Simoncini, 2013). Aside from causing lower abdominal pain and difficulties at voiding (Fritel, Varnoux, Zins, Breart, & Ringa, 2009), symptomatic uterine prolapse has been reported to worsen women's overall QOL (Fritel et al., 2009; Svihrova, Svihra, Luptak, Swift, & Digesu, 2014). In fact, uterine prolapse accounts for estimated loss of 217.0 disability-adjusted life years (DALYs) per 1000 women at age 50 years and 324.8 DALYs per 1000 women at age 60 years (Svihrova et al., 2014). Results from prospective cohort studies documented significant improvements in overall QOL after reconstructive surgery of the uterine prolapse (Bartuzi, Futyma, Kulik-Rechberger, & Rechberger, 2013), suggesting that surgical management of this condition is relatively simple and successful.