Breast tension

Breast tension

A new estrogen gel: clinical benefits

Published in Barry G. Wren, Progress in the Management of the Menopause, 2020

One important factor that has an influence on compliance is the occurrence of adverse events. Breast tension is one of the most common adverse drug reactions to estrogen replacement therapy. In the study of Kesäniemi and colleagues, breast tension was reported by 20% of the patients treated with the 1.0 g dose of the gel, but by 35% of those treated with 2 mg of oral estradiol valerate (Kesâniemi, unpublished data, 1996). In the study comparing the gel and a patch, the reported incidence of breast tension was lower, 7% and 3%, respectively (Hirvonen, unpublished data, 1993).

Overview of perimenopausal contraception

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Journal Information

Published in Climacteric, 2019

J. Bitzer

The main side-effects reported are bleeding irregularities, headache, mood swings, and breast tension. These side-effects are not harmful and frequently go away after 3–6 months34. Many women are especially concerned about weight gain. A Cochrane review found no causal association between COC and additional weight gain8,35.

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A new estrogen gel: clinical benefits

Overview of perimenopausal contraception