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The Role of Flaxseed Micronutrients and Nitric Oxide (NO) in Blood Vessel and Heart Function
Published in Robert Fried, Richard M. Carlton, Flaxseed, 2023
Robert Fried, Richard M. Carlton
This successive peristalsic stretch/distention and subsequent recoil pumps blood along in the circulatory system. The sole, albeit by no means lesser role of the heart in blood circulation is the ejection of the bolus from the left ventricle into the blood vessel. The key to how all this works, and therefore the key to blood pressure is “compliance,” i.e. the flexibility or distensibility of the vessel wall, i.e. the capacity to distend as a result of pressure from inside and then return to its original shape. Clearly, rigidity such as that due to atherosclerosis and other factors such as those related to aging impair compliance.
Role of Environmental Toxicants and Inflammation in Parkinson’s Disease
Published in Abhai Kumar, Debasis Bagchi, Antioxidants and Functional Foods for Neurodegenerative Disorders, 2021
Biddut Deb Nath, Dipti Debnath, Rokeya Pervin, Md. Akil Hossain
Rigidity: The stiffness or change of a muscle’s stiffness or tonicity is the second most frequent symptom found in PD patients. The PD patient mostly experiences being inflexible or tired, muscle and joint discomfort, and cramping. Quite often, muscle stiffness can develop resistance to the level that the individual experiences as if somebody else is shifting his or her joints.41
Chikungunya virus and Japanese encephalitis virus
Published in Avindra Nath, Joseph R. Berger, Clinical Neurovirology, 2020
As mentioned in Section 15.3.3, the vast majority of JEV infections are asymptomatic. Estimates of around 1% (0.1%–4%) [34] are clinically overt. The incubation period after the bite of an infected mosquito is around 1–2 weeks. Initial symptoms of fever, myalgias, chills, headache, and/or vomiting are nonspecific. Children commonly also have gastrointestinal symptoms. After several days, neurologic deterioration occurs. Level of consciousness becomes rapidly depressed and meningismus becomes apparent. Seizures, usually generalized, are common in both adults and children in some studies [37] and uncommon in adults in other reports [34]. Rigidity and paralysis may also accompany and are associated with poor prognosis. Parkinsonian features, especially hypomimia, cogwheeling, and tremor, are classically associated with the disease, and additional features, such as opisthotonus, dystonia, choreoathetosis, and opsoclonus-myoclonus, have also been associated. From there, progression can be to brainstem involvement and/or herniation. Indeed, respiratory and/or pupillary abnormalities, loss of oculocephalic reflexes, and abnormal posturing are all poor prognostic signs.
Post-arthrolysis rehabilitation in a patient with wrist stiffness secondary to distal radio-ulnar fracture: A case report
Published in Physiotherapy Theory and Practice, 2023
Andrea Inglese, Sheila Santandrea
Fractures of the distal epiphysis of radius and ulna are among the most frequent (Ilyas and Jupiter, 2007). In relation to the severity of the fracture, after a traumatic event, the choice is between a conservative and a surgical approach. The correct diagnosis and subsequent early treatment are essential to avoid possible long-term consequences (Mathews and Chung, 2015). The most frequent complications cited are neuropathies, arthritis, malunion and rigidity (Gutow, 2005). Among the secondary complications, rigidity is an occurrence that can be promoted by a period of prolonged immobilization (Ikpeze, Smith, Lee, and Elfar, 2016; Wong, 2002) which could cause the reduction of physiological joint excursion (Wong, 2002). Arthrolysis is a surgical technique that can be performed via open surgery or arthroscopy (Guidi et al., 2021) which allows immediate postoperative rehabilitation (Luchetti, Atzei, and Fairplay, 2007; Luchetti, Atzei, and Papini Zorli, 2006). Since a wrist arthrolysis rehabilitation guideline was not available in the literature yet, it was suggested that the main goals for treatment should be maintenance of passive wrist range of motion (PROM), reduction of pain, as well as improvement of functional active range of motion (AROM) and social reintegration.
Encouraging hindsight in advance: Age progression in therapy – and life
Published in American Journal of Clinical Hypnosis, 2022
Some therapies are clearly past oriented in their structure, placing a heavy emphasis on childhood developmental processes, attachment histories, and significant past events as presumed determinants of current problems in a person’s life. Other therapies are more structurally oriented to the present, paying much less attention to historical causes of client problems and much more attention to the “here-and-now” life circumstances and their consequences as experienced in-the-moment. And, some therapies are structurally oriented to the future, focusing on variations of this key question: what can I do or say now to interrupt the rigidity of this person’s symptomatic patterns in order to introduce flexibility and thereby facilitate a therapeutic outcome, i.e., a new and better response tomorrow?
Fatal serotonin syndrome: a systematic review of 56 cases in the literature
Published in Clinical Toxicology, 2021
Sanjay Prakash, Chaturbhuj Rathore, Kaushik Rana, Anurag Prakash
Seizure is not reported as a common manifestation in most of the reviews on SS. The prevalence of seizures varies from 2 to 5% in different reviews [53, 61]. In this review, convulsions were observed in 20 patients (36%), and it was the second most common symptom, again indicating that it may be a poor prognostic factor. The muscle rigidity is considered less common and less severe with SS compared to NMS [56]. Sternbach’s criteria did not include rigidity as a clinical feature. Although rigidity/hypertonicity is a part of the Hunter criteria, it was not a very common and prominent symptom in their database. They considered the presence of rigidity in severe and life-threatening SS [5]. Rigidity was noted in about 27% of our cases, and it was severe in many cases, leading to trismus, hyperextended spine and legs, opisthotonus, and inelicitable deep tendon reflex/clonus. Identification of trismus is very important as these patients may need an urgent tracheostomy. Our observation indicates that severe rigidity can occur in patients with severe SS and is again a poor prognostic factor. This can also cause diagnostic confusion with NMS.