China
Africa
Explore chapters and articles related to this topic
Hyperkinetic Movement Disorders
Published in Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw, Hankey's Clinical Neurology, 2020
Morales-Briceno Hugo, Victor S.C. Fung, Annu Aggarwal, Philip Thompson
Oromandibular dystonia: Onset 50 years.Women more commonly affected than men.Masticatory—jaw opening > closing.Facial grimacing 30% (including platysma).Pharyngeal, lingual, and cervical muscles may be affected.Initially triggered by eating, speaking.Mostly idiopathic.A common manifestation of tardive dystonia and some genetic dystonias.
Movement Disorders
Published in John W. Scadding, Nicholas A. Losseff, Clinical Neurology, 2011
Blepharospasm refers to recurrent spasms of eye closure. The periocular muscles forcibly contract for seconds or minutes, often repetitively, and can render the patient functionally blind. Such eye spasms are commonly precipitated by reading or watching television, or by bright lights. Oromandibular dystonia (OMD) refers to similar recurrent spasms of muscles of the mouth, tongue and jaw. Blepharospasm and OMD commonly coexist, when the condition is called cranial dystonia, or Meige’s or Breughel’s syndrome. Some patients with cranial dystonia may also exhibit torticollis or writer’s cramp (segmental dystonia).
Application of botulinum toxin in pregnancy and its impact on female reproductive health
Published in Expert Opinion on Drug Safety, 2020
Oromandibular dystonia (OMD) is a focal dystonia that affects the mouth, face, and jaw. Symptoms include persistent or repetitive involuntary jaw and tongue movements caused by chewing; facial, pharyngeal, tongue, and lip muscle contraction; and facial paralysis [22–25]. Therefore, this type of dystonia may affect oral and facial functions to varying degrees of severity. OMD affects the patient’s chewing and swallowing function, as well as facial expressions and communication. OMD is a rare disease with an incidence rate of less than 30 per 100,000 population [26]. The majority of patients are women, especially aged between 50 and 60 years [27]. Currently, BoNT injection is considered the preferred treatment for OMD [28]. Morgan reported a case of treatment of OMD with BoNT during pregnancy; that patient achieved symptom relief and gave birth to a healthy baby [20]. The only caveat with respect to BoNT injection for OMD is that there have been few reported cases of pregnant women with OMD treated in this manner, and no new epidemiological studies.
Cervical dystonia: factors deteriorating patient satisfaction of long-term treatment with botulinum toxin
Published in Neurological Research, 2020
Michał Marciniec, Anna Szczepańska-Szerej, Konrad Rejdak
Decreased long-term treatment efficacy was reported by 20.7% of CD patients. Factors which aggravated satisfaction of BoNT therapy were cervical pain and coexistence of oromandibular dystonia. Unsatisfactory treatment effectiveness was associated with higher scores of Tsui and TWSTRS scales.