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Chronic paronychia
Published in Robert Baran, Dimitris Rigopoulos, Chander Grover, Eckart Haneke, Nail Therapies, 2021
A pilot study was conducted to assess the role of 1064 Nd:YAG laser for the treatment of chronic paronychia. The results demonstrated that seven of eight patients showed an apparent clinical improvement without side effects, and therefore Nd:YAG laser therapy seems to be an alternate promising and safe method.
Upper gastrointestinal malignancy: palliation with thermal laser, photodynamic therapy and argon beamer
Published in David Westaby, Martin Lombard, Therapeutic Gastrointestinal Endoscopy A problem-oriented approach, 2019
The major consideration for many Units will be the initial capital outlay and subsequent running costs of thermal lasers, dye lasers or APC. A Nd-YAG laser costs £50 000 to £60 000 and a diode laser in excess of £45 000, though this is likely to drop significantly as diode technology rapidly advances. Dye lasers vary widely in price, between £45 000 to £70 000, and combined thermal/dye laser instruments are available at about £90 000. If these expensive instruments are placed in a central location and used in other specialties, e.g. thoracic medicine, urology, gynaecology and surgery, then the expense can more readily be justified. As photodynamic therapy establishes and extends its role in oesophageal cancer palliation, serious consideration should be given to the acquisition of one of the recently developed multi-wavelength capability non-laser light sources which are likely to be priced at about £10 000. Although styled as (readily) tunable, most dye lasers operate at a narrow band wavelength, whereas the non-laser instruments have the facility of rapid replacement of a filter to provide light wavelength for a wide range of photosensitizers.
Laser Photocoagulation: Experimental And Clinical Studies
Published in John P. Papp, Endoscopie Control of Gastrointestinal Hemorrhage, 2019
Fred E. Silverstein, David A. Gilbert, Andrew D. Feld, Robert L. Protell
Laser photocoagulation using the argon and Nd:YAG lasers has been studied fairly extensively in animal models of gastrointestinal bleeding. Controlled clinical trials are now underway in patients with upper gastrointestinal bleeding. Hopefully, these trials will define the exact benefit of laser photocoagulation for bleeding patients in terms of a reduction in morbidity, mortality, transfusions, and duration of hospitalization, as well as the risk of laser treatment. These studies of the argon and Nd:YAG lasers should be completed prior to the widespread clinical use of these expensive and potentially hazardous techniques.
Our experience using 1064 nm Nd:YAG in palmoplantar warts
Published in Journal of Cosmetic and Laser Therapy, 2022
Hai Thi Thu Le, Cuong Truong Van, Minh Nguyen Thi, Firas Al-Niaimi
Bingol et al. reported a clearance rate of 100% with a pulse width of 23 ms, fluence range of 180–200 J/cm2, and a spot size of 3 mm (15). Meanwhile, Han et al. also reported a rate for treating common warts (96%) but they had quite extensive side effects under their protocol with a pulse width of 20 ms, a higher fluence of 200 J/cm2, and a spot size of 5 mm. The main side effects encountered with Nd:YAG laser included transient pain during treatment (82%), post-treatment numbness (15%), hemorrhagic bullae (7%), hyperpigmentation (5%), and hypopigmentation (4%)(12). To minimize these side effects, Kimura et al. used a protocol with a shorter pulse width of 15 ms and a lower fluence range of 150–185 J/cm2. In Kimura’s study, a lower clearance rate of 56% was achieved, but with no remarkable side effects (13). However, one of the main advantages of the Nd:YAG laser was the absence of HPV DNA after treatment in comparison with cryotherapy (96%) and untreated cases (100%) (5).
Evaluation of the safety and efficacy of long pulsed Nd: YAG laser in the treatment of vascular lesions in vivo
Published in Journal of Cosmetic and Laser Therapy, 2022
Yun-Hee Rhee, Han-Yong Ryu, Jin-Chul Ahn, Phil-Sang Chung
532 nm of long pulse Nd:YAG laser was performed at fluences of 7.5 and 12 J/cm2 on the dorsal skin of nude mice. Figure 2 shows the histology of the dorsal skin in nude mice after the laser treatment. The Nd:YAG laser therapy at a wavelength of 532 nm showed no side effects such as edema, burns, or erythema in the epidermal tissues regardless of the laser pulse duration. We also observed the blood vessel disruption effect of a 532 nm long pulse laser on the dorsal skin of mice. 532 nm of long pulse laser treatment at a fluence of 12 J/cm2 disrupted the cutaneous vascular that were visually confirmed before laser treatment regardless of pulse duration (Figure 3a,b) However, a fluence of 7.5 J/cm2 of 532 nm did cause RBC extravasation and hemorrhage occasionally (black square indication). As shown in Figure 3c, the vessels in mice #1 and #2 were disrupted, but those in mice #3–#5 were preserved.
Short-term effects of an erbium/neodymium laser combination in superficial dyspareunia: a pilot study
Published in Climacteric, 2022
The neodymium:YAG (Nd:YAG) laser is a solid-state crystal laser-emitting light with a wavelength of 1064 nm that has a deeper optical penetration into tissue. The Nd:YAG laser is one of the most versatile and interesting lasers in dermatological laser medicine, having a wide spectrum of applications. Depending on the wavelength and mode, the Nd:YAG laser can be used for benign pigmented lesions (tattoos, traumatic tattoos, cafe-au-lait macules, lentigines), epilation and vascular lesions (teleangiectasias, hemangiomas). With its long pulses and durations in the range of seconds (PIANO mode), the Nd:YAG laser is ideal for homogeneous bulk heating of the tissues, such as the dermis or the subcutaneous fat. In the PIANO mode, with long pulse duration in the range of seconds, deeper structures can be reached in a very gentle, practically painless way. The PIANO mode has been successfully used for esthetic and dermatological indications, including lichen sclerosus treatment [16,17]. The combination of Er:YAG and Nd:YAG lasers has been demonstrated to be effective for non-invasive dermatologic and esthetic indications [16,18,19]. Therefore, the characteristics of the Nd:YAG laser in the PIANO mode could be of help also in treating the vulva and particularly the posterior commissure in PMW suffering from GSM. The aim of our pilot study was to investigate the efficacy of combined VEL and Nd:YAG laser treatment in PMW suffering from GSM with superficial dyspareunia.