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Inflammatory rheumatic disorders
Published in Ashley W. Blom, David Warwick, Michael R. Whitehouse, Apley and Solomon’s System of Orthopaedics and Trauma, 2017
Viral arthritis Viral infections are often associated with a transient polyarthralgia; flu-like illness and a rash will suggest the diagnosis. However, some infections – most typically parvovirus B19 – occasionally cause a symmetrical polysynovitis (including the finger joints) and early morning stiffness, symptoms which may last for several months or may recur over a few years. The absence of ‘rheumatoid’ X-ray features and subcutaneous nodules will raise suspicions about the diagnosis.
Joint pain
Published in Anne Stephenson, Martin Mueller, John Grabinar, Janice Rymer, 100 Cases in General Practice, 2017
Anne Stephenson, Martin Mueller, John Grabinar, Janice Rymer
The differential diagnosis includes rheumatoid arthritis; connective tissue diseases such as systemic lupus erythematosus (SLE); and osteoarthritis (with perimenopausal symptoms and mild anaemia, perhaps as a result of her menorrhagia). Gout usually affects one joint initially and there are no symptoms of a viral arthritis, one of the spondarthritides or psoriatic arthropathy.
Exploring the rationale for thermotherapy in COVID-19
Published in International Journal of Hyperthermia, 2021
Javier Mancilla-Galindo, Norma Galindo-Sevilla
Local thermotherapy has been used to treat rheumatic diseases. While thermotherapy does not modify objective measures of disease activity in rheumatoid arthritis (joint swelling, pain, medication intake, range of motion, grip strength, and hand function), it is still recommended as an adjuvant measure for its safety profile (does not cause harm to patients) [91]. Cryotherapy in osteoarthritis has been mostly studied as a beneficial therapy modality for patients, whereas heat-based thermotherapy is not supported by the small clinical studies done; clinical studies of thermotherapy in osteoarthritis are scarce [92]. Local thermotherapy could be particularly useful for patients with viral arthritis since higher temperatures enhance type I IFN responses in the affected joint [93]; clinical studies in humans are needed to address this hypothesis. Local thermotherapy could have an important role in the treatment of viral diseases for its ability to increase type I and II IFN and IFN-dependent signaling pathways [94].