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Fungi and Water
Published in Chuong Pham-Huy, Bruno Pham Huy, Food and Lifestyle in Health and Disease, 2022
Chuong Pham-Huy, Bruno Pham Huy
Occupational mycoses are professional forms of extrinsic allergic alveolitis. They are all inflammatory reactions caused by breathing high concentrations of mold spores and other antigenic organic matter (130). Some forms of these human diseases have been associated particularly with exposure to high concentrations of Aspergillus spores, including farmer’s lung, malt worker’s lung, compost lung, and bird fancier’s lung. Malt worker’s lung, one of the best known of these, is an occupational mycosis encountered during beer manufacture correlated with inhalation of high levels of Aspergillus clavatus and A. fumigatus spores from contaminated barley (130).
Hypersensitivity Pneumonitis
Published in Lourdes R. Laraya-Cuasay, Walter T. Hughes, Interstitial Lung Diseases in Children, 2019
The inhalation of and sensitization to antigens found in a wide variety of organic dusts originating from many different sources can result in hypersensitivity pneumonitis. The offending antigen can be bacterial (Thermophilic actinomyectes), fungal (Alternaria or Phoma species, Aspergillus clavatus, Penicillium frequentans, caseii, and roqueforti, Mucor sto-lonifer, and Cryptostroma corticate), animal proteins (dove, parakeet, parrot, pigeon, gerbil, bovine, porcine, or rat), chemicals (anhydrides, diisocyanates), other agents (amoeba, various fungi, Bacillus subtilis) and unknown agents in coffee dust.14 The Thermophilic actinomycetes, bacteria less than 1 μ with the morphology of fungi, are ubiquitous in soil, grain, and compost which contaminate moldy vegetation and forced-air heating and cooling systems. Microorganisms in this group responsible for HP seen in farmer’s lung, bagassosis, and ventilation pneumonitis are Micropolyspora faeni, Thermoactinomyces sacchari, and Thermoactinomyces Candidus respectively. Contaminated home humidifiers in forced-air heating or air-conditioning systems are another source of exposure to organic antigens from amebae and other fungi.
Respiratory
Published in Ashley Bond, MRCP Part 2 Examination, 2017
IgG mediated. Farmer’s lung – Micropolyspora faeni.Bird fancier’s lung – avian serum proteins, present in faeces.Bagassosis – Thermoactinomyes sacchari (sugar cane workers).Malt worker’s lung – Aspergillus clavatus.Mushroom worker’s lung – Thermophilic actinomycetes.
Synthesis and evaluation of novel benzimidazole derivatives as potential anti bacterial and anti fungal agents
Published in Egyptian Journal of Basic and Applied Sciences, 2021
Vishwajeet Amarsingh Pardeshi, Sultan Pathan, Amit Bhargava, Narendra Singh Chundawat, Girdhar Pal Singh
Compounds 3b,3 g,3 l,3q with MIC value 23 μg/mL exhibited twofold more activity compared with standard drug Griseoulvin and compounds 3a,3e,3 h,3 j,3k,3o and 3 r with having MIC value 21 μg/mL each which is very close to the twofold activity of the standard drug. For the compounds 3 c, 3 m and 3i, 3s with MIC value 24 μg/mL and 19 μg/mL showed good activity compared with Griseoulvin drug, respectively, against fungicidal strains Candida albciacnas. Compounds 3a, 3d, 3i, 3k, 3 m, 3s with MIC 21 μg/mL exhibited twofold more activity compared with standard drug Griseoulvin. In addition, 3 h,3 r showed 17 μg/mL 3 f,3p showed 18 μg/mL 3 g,3q 19 μg/mL 3e,3 j and 3o exhibited 20 μg/mL and finally 3b,3 l showed 22 μg/mL, which very close to onefold against fungicidal strains Aspergillus Clavatus (Table 3).
Biosensors for the detection of mycotoxins
Published in Toxin Reviews, 2022
Akansha Shrivastava, Rakesh Kumar Sharma
Patulin was first isolated as a substance with antimicrobial properties but later in 1960s found toxic to animals and plants. The disease called "Blue mold", common in apple, pear, cherry, and other fruits is caused by the fungus Penicillium expansum, which is also considered an efficient producer of patulin naturally. It is reported to damage the immune system of animals. Other immense producer fungi are Aspergillus clavatus, Aspergillus giganteus, and Aspergillus terreus (Edite Bezerra da Rocha et al. 2014, Ioi et al. 2017). Varied patulin levels have been detected in different fruits (apple and grapes) and fruit juices being highest in apple leather 2259 µg/kg (Saleh and Goktepe 2019).
Role of mycotoxins in the pathobiology of autism: A first evidence
Published in Nutritional Neuroscience, 2019
Barbara De Santis, Carlo Brera, Alessandra Mezzelani, Sabina Soricelli, Francesca Ciceri, Giorgio Moretti, Francesca Debegnach, Maria Clara Bonaglia, Laura Villa, Massimo Molteni, Maria Elisabetta Raggi
Mould- and food-specific IgG antibodies (against Alternaria tenuis, Aspergillus clavatus, Asp. flavus, Asp. fumigatus, Asp. nidulans, Asp. niger, Asp. oryzae, Asp. terreus, Candida albicans, Cladosporium herbarum, Fusarium moniliforme, Pennicillium brevicompactum and P. notatum, carrot, celery, cod fish, egg white, gluten, honey, α-lactalbumin, β-lattoglobulin, orange, peanut, wheat, yolk) were assessed by the Immulite 2000 XPi automated system with an ‘allergen-Specific IgG’ test on a solid-phase, enzyme-labelled chemiluminescent immunometric assay. Chemiluminescent signal was measured as proportioned to the bound enzyme (Standard WHO 1st IRP 67/86).