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Eating Disorders (EDs)
Published in S Paige Hertweck, Maggie L Dwiggins, Clinical Protocols in Pediatric and Adolescent Gynecology, 2022
TSH as screen sufficient, as thyroid function tests likely to reveal euthyroid sick syndrome with decreased peripheral conversion of thyroxine (T4) to T3 and high or high normal reverse T3—an adaptation to starvation to reduce metabolic rate
Biochemistry
Published in Burkhard Madea, Asphyxiation, Suffocation,and Neck Pressure Deaths, 2020
Situations of thyroid storm following local pressure to the neck caused by strangulation or suicide attempts by hanging have been exceptionally observed. Ramírez et al. [56] reported the case of a 37-year-old woman, without pre-existing thyroid disease, who was admitted to hospital after being assaulted. At the scene, she was found with a tourniquet tied around her neck. At admission, physical examination revealed a circumferential cervical contusion along with cervicofacial ecchymoses and petechiae. Plasma thyroid function tests showed TSH concentration below 0.01 mU/l (normal range 0.5–4.5 mU/l) and T4 concentration at 19.3 μg/dl (normal range 5.0–12.0 μg/dl). TSH concentration before strangulation was retrospectively determined and was normal, thus supporting the diagnosis of thyroid storm induced by local pressure to the neck in a previously euthyroid patient.
Endocrine emergencies with skin manifestations
Published in Biju Vasudevan, Rajesh Verma, Dermatological Emergencies, 2019
The diagnosis of thyroid disease is confirmed by thyroid function tests. Screening is done with serum levels of TSH, and any abnormalities in TSH should be followed by measurements of serum free T4 and T3 and antithyroid antibodies.
Mechanical circulatory support for thyrotoxicosis-induced cardiomyopathy
Published in Baylor University Medical Center Proceedings, 2023
Nikita Dhir, Travis Haneke, Timothy Mixon
Thyrotoxicosis is a serious condition that can lead to high-output heart failure and possible cardiogenic shock.1 It usually presents with extreme symptoms of hyperthyroidism, including tachycardia, fever, hypotension, agitation, nausea, vomiting, and/or diarrhea. Thyroid function tests will show high free T4 and T3, with low thyroid-stimulating hormone. Treatment for thyroid storm includes beta-blockers, iodine solution, thionamides, and glucocorticoids.2 Complications of heart failure can potentially require temporary mechanical circulatory support (MCS) with an Impella device or extracorporeal membrane oxygenation (ECMO).1 In patients with hemodynamic instability, beta-blockers are avoided to prevent worsening of high-output cardiac failure. MCS can be a useful bridging tool during the treatment of reversible causes of cardiogenic shock, such as thyroid storm.
Thyroid disorders and pathospermia in the ART clinic patients
Published in Gynecological Endocrinology, 2021
T. V. Lisovskaya, O. S. Dubrovina, I. M. Treshchilov, L. B. Senturina, O. Y. Sevostyanova, E. N. Mayasina, Yu. E. Buev, D. F. Salimov
A total of 168 men of infertile marriage were examined in the ART clinic from November 2020 to April 2021. Men with male infertility factor associated with erectile dysfunction and normospermia (9 patients, 5.3%) were excluded. The study included 159 men and the patients were divided into three groups: the 1st study group consisted of men with non-obstructive azoospermia − 11 men (6.9%); the 2nd study group included men with other forms of pathospermia − 38 men (23.9%) and the control group consisted of men in infertile marriage with normospermia − 110 men (69.2%). The median age of men with various azoospermia was 31.5 (29.25 ÷ 41) and 35 (32.5 ÷ 38) years in the study groups of patients with non-obstructive azoospermia and oligoasthenoteratozoospermia, respectively, and did not differ from the control group − 35 (33 ÷ 39.25) years, р>.05. All patients had anthropometric measurements, laboratory tests, thyroid and testicular ultrasonography. Spermogram was analyzed in accordance with the WHO classification, 5th revision, 2010. Thyroid function tests included TSH, free thyroxine (FТ4), thyroperoxidase antibodies (anti-TPO) and thyroid ultrasonography (US).
Effects of methadone, opium tincture and buprenorphine maintenance therapies on thyroid function in patients with OUD
Published in Journal of Addictive Diseases, 2020
Habibesadat Shakeri, Reihaneh Hejrati, Seyed Kaveh Hojjat, Mina Norozi Khalili, Tooba Farazmand, Samaneh Mollazadeh
In the first stage, investigators obtained written informed consent from the participants after a briefing session. Then, demographic information and medical history were collected through interviews with patients, and the data were collected in a designed entry form which was composed of three parts. The first part contained patient demographic information. The second part included details of the patient history (including the history of any underlying disease). The last section included medication history such as the type of prescribed drugs, the type of maintenance treatment, and the duration of treatment. Subsequently, the thyroid function of the patients was examined physically by endocrinologist. To do so, all patients were referred to a distinct laboratory and underwent thyroid measurements that included serum levels of fT3, fT4, TSH, T3RU, and Anti TPO. Besides, liver enzymes (AST, ALT) and CBC were also measured. Patient receiving maintenance therapy also received hepatic and blood tests every three months. Therefore, the thyroid function tests were added to the routine tests of the patients. Thyroid function tests were performed by electrochemiluminescence with a Cobas 411 analyzer (ECL) at the contractor laboratory. Finally, the laboratory data were recorded in a specific checklist. To comply with the research ethics and privacy norms, all checklists were kept anonymous.