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Conditions
Published in Sarah Bekaert, Women's Health, 2018
This condition is characterised by excessive activity of the pituitary gland, especially overactivity of the anterior lobe (which leads to excess secretion of growth hormone). Although a certain amount of growth hormone is needed by the body for normal regulatory functions, too much results in the abnormal growth of hands, feet and internal organs (acromegaly). Hyperpituitarism is usually caused by a tumour.
Endocrine system
Published in Brian J Pollard, Gareth Kitchen, Handbook of Clinical Anaesthesia, 2017
Brian J Pollard, Gareth Kitchen
Hypopituitarism is a common sequel of pituitary surgery, but can also be due to pressure from a primary pituitary tumour. Other causes include brain surgery, postpartum pituitary necrosis (Sheehan syndrome), extrasellar tumours, infection, hypoperfusion or radiotherapy. Hypopituitarism is a common and clinically relevant complication of traumatic brain injury and should be actively searched for in these patients. Diagnosis may be confirmed by circulating hormone levels or by functional tests such as lack of response of GH to hypoglycaemia, of ACTH to corticotropin releasing hormone (CRH), of TSH to thyrotrophin releasing hormone (TRH), or alleviation of polyuria by desmopressin. Hyperpituitarism is nearly always due to tumours or hyperplasia of the secretory cells.
Investigation on aetiological factors in patients with hyperhidrosis
Published in Cutaneous and Ocular Toxicology, 2018
Secondary hyperhidrosis (Secondary HH) occurs due to an underlying systemic disease or drug use. It can either be observed as localized asymmetric patches or generalized sweating3,6. While endocrine disorders such as hyperthyroidism, diabetes mellitus, phaeochromocytoma, hyperpituitarism and some conditions such as acute and chronic infections, congestive heart failure, respiratory failure, drug withdrawal syndrome, gout, alcohol intoxication and Parkinson’s disease usually cause generalized hyperhidrosis, localised hyperhidrosis occurs due to blue rubber bleb naevus syndrome, sudoriferous angioma, and various skin tumours such as glomus tumour2,8,14,17.
Ocular manifestations of endocrine disorders
Published in Clinical and Experimental Optometry, 2022
M Hossein Nowroozzadeh, Sarah Thornton, Alison Watson, Zeba A Syed, Reza Razeghinejad
When a chiasmal disorder is suspected, patients should be asked about symptoms of endocrine dysfunction. Sellar masses may cause hypopituitarism from damage to normal pituitary tissue, or hyperpituitarism if a hormone-secreting pituitary adenoma is present. Men may be questioned about gynecomastia and erectile dysfunction, and women may be asked about menstrual cycle abnormalities and galactorrhoea. Other symptoms include changes in weight, libido, and urinary frequency.22 Patients with non-secreting tumours are more likely to present later with headache and vision loss from mass effect.81