China
Africa
Explore chapters and articles related to this topic
Managing Crush Injuries on Arrival
Published in Kajal Jain, Nidhi Bhatia, Acute Trauma Care in Developing Countries, 2023
Sarvdeep Singh Dhatt, Deepak Neradi
Crush syndrome can occur in any patient with blunt injury to any muscle compartment. Patients with these kinds of injuries should be monitored closely and are resuscitated as early as possible. There are various options in the management, including fluid resuscitation, alkaline therapy, dialysis and hyperbaric oxygen. Early management is the key to good outcome.
Mechanism of Injury
Published in Ian Greaves, Keith Porter, Jeff Garner, Trauma Care Manual, 2021
Ian Greaves, Keith Porter, Jeff Garner
Crush injuries sustained to the torso or head are frequently fatal due to the magnitude of force, thus injuries appear to be more common in the extremities. Extremity crush injury can be followed by crush syndrome, a secondary injury resulting from the development of a combination including: compartment syndrome, rhabdomyolysis, renal failure and reperfusion injury. Crush syndrome must be considered and mitigated through prompt recognition and treatment.52
Adult Autopsy
Published in Cristoforo Pomara, Vittorio Fineschi, Forensic and Clinical Forensic Autopsy, 2020
Cristoforo Pomara, Monica Salerno, Vittorio Fineschi
Key PointsCrush syndrome is a complication known to most, but infrequent and, therefore, rarely suspected in the management of the multitrauma patient.In such cases, it is crucial to quickly diagnose in order to avoid the most feared complications: hypovolemic shock and acute renal failure.The diagnosis of crush syndrome must be made on the basis of clinical evidence and data obtained from the laboratory tests.The latter should include the search for biohumoral alterations induced by rhabdomyolysis (myoglobinemia and myoglobinuria, increased creatinine phosphokinase, hydroelectrolyte, and metabolic alterations).
Protective effect of thymol on glycerol-induced acute kidney injury
Published in Renal Failure, 2023
Qinglian Wang, Guanghui Qi, Hongwei Zhou, Fajuan Cheng, Xiaowei Yang, Xiang Liu, Rong Wang
Acute kidney injury (AKI), previously known as acute renal failure (ARF), was first replaced by the emergency medical community and the international society of nephrology [1] and is a syndrome characterized by an accelerating decrease in renal function in a short time. It is a crucial clinical problem with a high mortality rate, prolonged hospital stays and accelerated chronic kidney disease. Generally, the onset of AKI is hidden until the body cannot tolerate natremia [2]. Once diagnosed, the mortality of AKI is as high as 50% in the intensive care unit [3], and effective therapy to reverse or prevent progression is rarely mere. Rhabdomyolysis (RM)-induced AKI is named RM-mediated myoglobinuric renal damage, with 15% of all RM patients accounting for 40% of AKI cases [4]. It often develops after crush syndrome, exhaustive exercise, medications, infections, and toxins [5–8].
Immunomodulatory role of recombinant human erythropoietin in acute kidney injury induced by crush syndrome via inhibition of the TLR4/NF-κB signaling pathway in macrophages
Published in Immunopharmacology and Immunotoxicology, 2020
Jiaojiao Zhou, Yajun Bai, Yong Jiang, Padamata Tarun, Yuying Feng, Rongshuang Huang, Ping Fu
Crush syndrome (CS) is a critical clinical syndrome that is characterized by the prolonged compression of skeletal muscle to cause ischemic necrosis and is accompanied by limb swelling, hyperkalemia, myoglobinuria, and acute kidney injury (AKI) [1]. In all types of massive disasters, such as earthquakes, war, and landslides, life-threatening complications are the leading cause of survivor mortality [2]. AKI is a serious complication of crush injury that can be reversed. When renal failure occurs, the prognosis of AKI deteriorates significantly [3]. The mortality rate of CS-induced AKI is quite high. Previous studies showed that the mortality rate of CS-induced AKI during the Wenchuan earthquake in China was 10.96% (69,197 deaths, 374,176 injuries) [4,5].
2017 Bangladesh landslides: physical rehabilitation perspective
Published in Disability and Rehabilitation, 2021
Taslim Uddin, Mohammad T. Islam, James E. Gosney
A large proportion of direct physical health impacts due to landslides are deaths from suffocation and asphyxiation [12]. Injury associated with being struck by rock or other debris if not buried by the mass movement has been reported [13]. Due to significant debris weight loading, crush syndrome is common and is treatable if detected early. Severe traumatic injuries may be sustained and less serious musculoskeletal injuries are common. Significant mental health and psychosocial impacts from landslides also occur. Common indirect physical health effects include wound infections and post-disaster infectious and respiratory diseases [12]. In general, the health impacts of landslides are poorly studied [14].