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Syringocystadenoma papilliferum
Published in Longo Caterina, Diagnosing the Less Common Skin Tumors, 2019
There are few reports in the literature that describe dermoscopic features of syringocystadenoma papilliferum.8–14 The first description of SCAP associated with nevus sebaceous was reported by Bruno et al.9: they described a polymorphous vascular pattern in which some vessels were surrounded by a whitish halo and others were grouped in a horseshoe arrangement on a pinkish-white background.9 This pattern was also confirmed by Chauhan and colleagues.14
Tumors of Cutaneous Appendages
Published in Omar P. Sangueza, Sara Moradi Tuchayi, Parisa Mansoori, Saleha A. Aldawsari, Amir Al-Dabagh, Amany A. Fathaddin, Steven R. Feldman, Dermatopathology Primer of Cutaneous Tumors, 2015
Syringocystadenoma papilliferum: Prominent cystic invagination lined by squamoid and apocrine epitheliumProminent plasmacellular infiltrates in the stromaLocalization to the head and neck areaFrequent association with nevus sebaceus
Hidradenoma papilliferum of the perineum; a rare tumour in a rare location
Published in Journal of Obstetrics and Gynaecology, 2023
Saliha Sağnıç, Sinan Serdar Ay, Hasan Aykut Tuncer, Selen Doğan, Tayup Şimşek
Tumours of the apocrine gland are closely related to each other histopathologically. Tubular apocrine adenoma, clear cell (apocrine) hidradenoma, and syringocystadenoma papilliferum should be included in the histopathological differential diagnosis of HP. Syringocystadenoma papilliferum is very rarely seen in the female genital tract. Cystic invaginations extending downward from the epidermis along with plasma cell infiltration are characteristic of histological findings of syringocystadenoma papilliferum and the absence of connection in the papillary structure distinguishes hidradenoma papilliferum from syringocystadenoma papilliferum. GCDFP-15, a sensitive marker for apocrine differentiation, is mostly positive in HP while in syringocystadenoma papilliferum lower GCDFP-15 staining has been reported (Nishie et al. 2004). In tubular apocrine adenoma, tubules have a dilated lumen with papillary projections extending into it. In clear cell hidradenoma, the lesions are constructed with apocrine-like tubular structures and clear cells can be seen. Hidradenoma papilliferum sometimes displays histopathology similar to these conditions (Minami et al. 2006, Lee et al. 2011).
Eyelid syringocystadenoma papilliferum: A novel presentation with major review
Published in Orbit, 2018
Michael C Tseng, Bijal Amin, Anne Barmettler
Syringocystadenoma papilliferum (SCAP) is a benign adnexal tumor of the apocrine glands. It is most commonly found in the head and neck at birth or early age.1 Approximately one-third of these lesions develop in a preexisting nevus sebaceus. In the setting of a nevus sebaceous, up to 10% of SCAP lesions are associated with the development of basal cell carcinoma and more rarely other carcinomas, such as syringocystadenocarcinoma papilliferum (SCACP).2–4 SCAP is seldom found on the eyelid and has never been reported to cause corneal abrasion, as in this case report.
Multiple secondary neoplasms in nevus sebaceus excision
Published in Baylor University Medical Center Proceedings, 2022
Travis S. Dowdle, David A. Mehegran, Dylan Maldonado, Cort D. McCaughey
Nevus sebaceus is of particular clinical interest because of its association with the development of secondary neoplasms of varying rarity. Secondary tumors are typically benign, but malignant neoplasms have also been observed. The most common benign neoplasms include trichoblastoma and syringocystadenoma papilliferum. Additional benign neoplasms such as apocrine/eccrine adenoma, trichilemmoma, and sebaceoma have been observed.3 It has been estimated that approximately 40% of syringocystadenoma papilliferum lesions are associated with nevus sebaceus.4