China
Africa
Explore chapters and articles related to this topic
Lower legs
Published in Richard Ashton, Barbara Leppard, Differential Diagnosis in Dermatology, 2021
Richard Ashton, Barbara Leppard
Limb enlargement is associated with congenital vascular abnormalities such as a port wine stain, deeper cavernous vessels, arterio-venous fistulae or venous-lymphatic malformations. The limb enlargement is due to increased blood flow resulting in soft tissue and sometimes bone overgrowth. Typically, a port wine stain is obvious at birth or in early childhood. The limb hypertrophy occurs gradually later on.
Orthopaedics and musculoskeletal system
Published in Jagdish M. Gupta, John Beveridge, MCQs in Paediatrics, 2020
Jagdish M. Gupta, John Beveridge
14.14. A port-wine stain in an infant aged 1 month willbecome worse over the next 1-2 years then regress.indicate a risk of occurrence in 1 in 8 future siblings.remain permanently.probably become malignant if not excised during childhood.respond well to treatment with carbon dioxide snow.
Klippel−Trenaunay Syndrome
Published in Dongyou Liu, Handbook of Tumor Syndromes, 2020
A diagnosis of KTS can be made when two of the following three features are met: (i) cutaneous capillary malformations (port-wine stain), (ii) bone and soft tissue hypertrophy, (iii) varicose veins (venous and lymphatic malformations mainly on the extremities and the adjacent pelvis or shoulder) [26,27]. Molecular identification of PIK3CA pathogenic variants provides further confirmation of the disorder.
Topical photodynamic therapy with 5-aminolevulinic acid in Chinese patients with Rosacea
Published in Journal of Cosmetic and Laser Therapy, 2019
Yan Sun, Lianghong Chen, Yuhui Zhang, Xinghua Gao, Yan Wu, Hongduo Chen
PDT has numerous antineoplastic, anti-inflammatory, and anti-microbial effects (19). In the treatment of condylomata acuminata and skin carcinoma, PDT induces necrosis/apoptosis in dysplastic/neoplastic cells and influences tumor microvasculature. Additionally, it generates high levels of reactive oxygen species to induce potent vascular damage and hypoxia. PDT has also proven to be effective in the treatment of port-wine stain. In this condition, the photosensitizer is activated by light at an appropriate wavelength, and it circulates in blood vessels. Selective photodynamic damage to the walls of vessels associated with port-wine stain ultimately closes the vessels and causes blanching without destruction of surrounding skin tissue (20,21). The photosensitizer used to treat port-wine stain is hemporfin, which is different from ALA. However, another study showed that ALA is also effective for vessels (22). To treat rosacea, especially ET rosacea, vessels may be destroyed partially or totally by PDT, thus alleviating or even eliminating erythema and/or telangiectasia.
Treatment of port wine stains with 595-nm pulsed dye laser in 27 pediatric patients: A prospective study in the Iranian population
Published in Journal of Cosmetic and Laser Therapy, 2019
Ali Sadeghinia, Saba Moghaddas, Soheil Tavakolpour, Amir Teimourpour, Maryam Danespazhooh, Hamidreza Mahmoudi
Port wine stain (PWS) is a cutaneous congenital vascular malformation affecting males and females and all racial groups equally. It is characterized by pink to erythematous skin patches, especially on the face and neck; and has a low incidence of 0.3%–0.5% of the newborn (1). Although its exact etiology has remained unclear, PWS develops as the result of ectatic capillaries in the skin. Most of PWS cases are sporadic, although familial PWS have been described in the literature (2) which suggests the role of genetic background in its development. For example, the somatic variation in specific genes, such as GNAQ has been shown as a factor for the development of PWS (3,4). In spite of being harmless, it can be associated with important cosmetic and psychological implications.
Editorial
Published in Journal of Cosmetic and Laser Therapy, 2018
This edition of the Journal contains many innovative fascinating studies. The first study relates to female vaginal rejuvenation with a radiofrequency device. This new approach has now become part of the aesthetic mainstream and we will see many more studies about this innovative approach. The next study describes a retrospective analysis of the influencing factors and complications of Q-switched lasers in tattoo removal in China. This is followed by studies looking at a prospective analysis of the port-wine stain patient population in the Netherlands in light of novel treatment modalities; gingival melanin depigmentation with an Er:YAG laser; and comparing the effectiveness of laser vs. conventional endoforehead lifting.