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Schimmelpenning–Feuerstein–Mims Syndrome
Published in Dongyou Liu, Handbook of Tumor Syndromes, 2020
Differential diagnoses of nevus sebaceous include aplasia cutis congenital or mastocytomas (early infant lesion); congenital nevi, epidermal nevus, seborrheic keratosis, verruca, and juvenile xanthogranulomas (later-stage lesion); phakomatosis pigmentokeratotica (known as speckled lentiginous nevus of the papular type; large, light-brown discoloration of the skin, superimposed by multiple darkened/melanocytic spots/papules), seizures, intellectual impairment, muscle weakness, paralysis on one side of the body (hemiparesis), underdevelopment of one side of the body (hemiatrophy), excessive sweating (hyperhidrosis), and cutaneous dysesthesia, abnormal side-to-side curvature of the spine (scoliosis), vitamin D-resistant rickets, short stature, propensity to fractures, hearing loss in one ear, crossed eyes (strabismus), droopy upper eyelid (ptosis), and narrowing of the aorta (aortic stenosis), rhabdomyosarcoma, postzygotic HRAS mutation [8,13], CHILD syndrome (congenital hemidysplasia with ichthyosiform nevus and limb defects), type 2 segmental Cowden disease, Proteus syndrome, fibroblast growth factor receptor 3 epidermal nevus syndrome (García-Hafner-Happle syndrome), nevus trichilemmocysticus syndrome, didymosis aplasticosebacea, SCALP syndrome (sebaceous nevus, central nervous system malformations, aplasia cutis congenita, limbal dermoid and pigmented nevus), Gobello syndrome, Bäfverstedt syndrome, NEVADA syndrome (nevus epidermicus verrucosus with angiodysplasia and aneurysms), and CLOVE syndrome (congenital lipomatous overgrowth, vascular malformations, and epidermal nevus) [14].
Syringocystadenoma papilliferum
Published in Longo Caterina, Diagnosing the Less Common Skin Tumors, 2019
Other dermoscopic features observed are a symmetric erythematous lesion with pink-white exophytic papillary structures followed by a central depression, erosions/crust/ulceration and vascular structures (hairpin vessels, polymorphous atypical vessels and common vessels).7 When it is associated with a nevus sebaceous, a yellow color is also detected (Figures 24.4 through 24.6).11,13
Tumors of Cutaneous Appendages
Published in Omar P. Sangueza, Sara Moradi Tuchayi, Parisa Mansoori, Saleha A. Aldawsari, Amir Al-Dabagh, Amany A. Fathaddin, Steven R. Feldman, Dermatopathology Primer of Cutaneous Tumors, 2015
Nevus sebaceous: Lobules are aberrantDucts open into the epidermisEpidermal hyperplasiaIn some cases presence of apocrine glands, trichoblastomas and syringocystadenoma papilliferum
Multiple secondary neoplasms in nevus sebaceus excision
Published in Baylor University Medical Center Proceedings, 2022
Travis S. Dowdle, David A. Mehegran, Dylan Maldonado, Cort D. McCaughey
Nevus sebaceus, also referred to as nevus sebaceus of Jadassohn and organoid nevus, is a congenital hamartoma composed of follicular, sebaceous, and apocrine structures and is associated with a number of secondary tumors of varying rarity. These lesions are primarily found on the head or neck, most notably the scalp.1 Approximately 0.3% of newborns are affected by nevus sebaceus, and the lesion does not show preference for gender or race.2 The lesion typically grows slowly with age, with the most rapid growth occurring during the pubertal hormonal surge.1 The two most common secondary neoplasms developing within a nevus sebaceus are trichoblastoma and syringocystadenoma papilliferum during or after puberty.3 Though other secondary neoplasms can and do occur within nevus sebaceus, it is extremely unusual to observe two distinct secondary tumors at once.
Eyelid syringocystadenoma papilliferum: A novel presentation with major review
Published in Orbit, 2018
Michael C Tseng, Bijal Amin, Anne Barmettler
Syringocystadenoma papilliferum (SCAP) is a benign adnexal tumor of the apocrine glands. It is most commonly found in the head and neck at birth or early age.1 Approximately one-third of these lesions develop in a preexisting nevus sebaceus. In the setting of a nevus sebaceous, up to 10% of SCAP lesions are associated with the development of basal cell carcinoma and more rarely other carcinomas, such as syringocystadenocarcinoma papilliferum (SCACP).2–4 SCAP is seldom found on the eyelid and has never been reported to cause corneal abrasion, as in this case report.