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Retinoids in Other Skin Diseases
Published in Ayse Serap Karadag, Berna Aksoy, Lawrence Charles Parish, Retinoids in Dermatology, 2019
Uwe Wollina, Piotr Brzezinski, André Koch
Linear IgA bullous dermatosis is a very rare bullous disease that can be further differentiated into intra-epidermal neutrophilic IgA dermatosis and subcorneal pustular dermatosis-type. There are two case reports on successful treatment with 35 mg acitretin/day either alone or in combination with 100 mg dapsone/day (58,59).
Dapsone for the treatment of acne vulgaris: do the risks outweigh the benefits?
Published in Cutaneous and Ocular Toxicology, 2022
Selami Aykut Temiz, Munise Daye
Dapsone is a “4,4′-diamino diphenyl sulfone” compound and an aniline derivative from synthetic sulphones. Sulphonamides were first synthesized as dyes (reproduced from coal) for the cloth industry in 1908. Sulphonamides were first used in humans as antimicrobial agents to treat streptococcal infections. Dapsone derived from sulphonamides was first used in the treatment of leprosy in 19401. Subsequently, it was used in the treatment of bullous dermatoses, especially dermatitis herpetiformis, and in the treatment of non-infectious inflammatory dermatoses, especially neutrophilic dermatoses1,2. Today, Dapsone treatment is among the treatment options for many dermatological diseases2,3. Furthermore, the dapsone treatment is recommended as the first treatment option for the therapy of dermatitis herpetiformis, subcorneal pustular dermatosis, linear IgA bullous dermatosis, and erythema elevatum diutinum3.
Vancomycin-induced linear IgA bullous dermatosis
Published in Baylor University Medical Center Proceedings, 2021
Claire J. Wiggins, Susan Y. Chon
Linear IgA bullous dermatosis (LABD) is a rare autoimmune disease characterized by subepidermal deposits of IgA. The clinical presentation of LABD varies, from vesicular lesions akin to herpetic disease to diffuse blisters similar to bullous pemphigoid, even occasionally manifesting as a mimicker of Stevens-Johnson syndrome or toxic epidermal necrolysis.1,2 Although most cases are deemed idiopathic, a subset of cases are known to be provoked by an infection, autoimmune disease, tumor, or medication.3,4 Here, we describe a case of vancomycin-associated LABD.
Diagnosing and managing patients with drug hypersensitivity
Published in Expert Review of Clinical Immunology, 2018
Javier Fernandez, Inmaculada Doña
In the differential diagnosis of these severe cutaneous reactions, clinicians should also consider another entity, acute generalized exanthematous pustulosis (AGEP) [97], as well as defined dermatological entities such as erythema multiforme, erythroderma and erythematous drug eruptions, generalized bullous fixed drug eruption (FDE), phototoxic eruptions, staphylococcal scalded skin syndrome, paraneoplastic pemphigus, and linear IgA bullous dermatosis.