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Disorders of Keratinization and Other Genodermatoses
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Roselyn Stanger, Nanette Silverberg
Overview: This is commonly seen in children and young adults, and children often have an involvement of their cheeks. In young children, background erythema of the cheeks can be noted, termed keratosis pilaris rubra faceii. Keratosis pilaris can be an isolated diagnosis and can also be seen in patients with underlying skin disorders, such as atopic dermatitis and ichthyosis vulgaris, among others. There is often a positive family history.
Transfollicular elimination of sebaceous glands in a patient with disseminate and recurrent infundibulofolliculitis
Published in Baylor University Medical Center Proceedings, 2021
Mahmud Alkul, Travis S. Dowdle, Jay Truitt, Michelle B. Tarbox
Differential diagnoses for DRIF include bacterial and fungal folliculitis, follicular eczema, keratosis pilaris, and truncal acne, among others.3 Although rare Pityrosporum yeast were demonstrated on biopsy, their presence in only some of the follicles make this diagnosis less likely. Follicular eczema is characterized by inflammatory infiltrate not limited to the infundibulum of the hair follicle.2 Keratosis pilaris is clinically significant for hyperkeratinization.2 Lesions may be differentiated from truncal acne vulgaris by histopathology revealing follicular dilation, increased sebum production, and accumulation of keratin.4 DRIF has been associated with other dermatologic conditions such as hidradenitis suppurativa, a chronic inflammatory disease of the pilosebaceous unit, especially in patients with trisomy 21.5
Dermatology for the internist: optimal diagnosis and management of atopic dermatitis
Published in Annals of Medicine, 2021
Shanthi Narla, Jonathan I. Silverberg
Age-related differences in AD presentation were observed. Compared to adult studies, paediatric studies reported a higher prevalence of dermatitis affecting eyelid, auricle, and ventral wrist; exudative eczema; seborrhoeic dermatitis-like features. Adults had a higher prevalence of lichenification, erythroderma, disease course influenced by emotions and/or environmental factors, ichthyosis (widespread and persistent thick, dry, “fish-scale” skin), palmar hyperlinearity, keratosis pilaris, hand and foot dermatitis, dyshidrosis, prurigo nodularis, and papular lichenoid lesions [37]. Keratosis pilaris is a common skin condition that causes dry, rough patches and tiny bumps, often on the upper arms, thighs, cheeks, or buttocks.
Classification and recommended treatment options for folliculotropic mycosis fungoides
Published in Expert Opinion on Orphan Drugs, 2018
Suzanne van Santen, Maarten H. Vermeer, Rein Willemze
Clinically, patients present with (grouped) follicular papules, acneiform lesions, infiltrated plaques and/or tumors, which preferentially involve and are most pronounced in the head and neck area [2–4,17–22]. Some patients may show keratosis pilaris-like lesions, mainly on extremities and trunk [12,22,23]. The skin lesions are often associated with alopecia. The presence of infiltrated plaques in the eyebrow region with concurrent alopecia is a common and highly characteristic feature. Patients often report pruritus and secondary bacterial infections are common. In rare cases, FMF may present with a solitary skin lesion (solitary or unilesional FMF) or with erythroderma.