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Vascular tumors
Published in Eckart Haneke, Histopathology of the NailOnychopathology, 2017
Whereas port-wine stains, other vascular malformations, and hemangiomas are very common in glabrous skin, they are exceptional in the nail region. Glomeruloid hemangioma, reactive angioendotheliomatosis, generalized essential telangiectasia, unilateral nevoid telangiectasia, angioma serpiginosum, nevus araneus, venous lake, senile angioma, tufted angioma, microvenular hemangioma, targetoid hemosiderotic hemangioma, acquired elastotic hemangioma, cutaneous epithelioid angiomatous nodule, and some other rare angiomatous lesions have not, to our knowledge, been observed in the nail apparatus or its immediate vicinity. Eruptive epithelioid hemangiomas were recently described in a patient with two of them growing under the nail and in the proximal nail fold, respectively.2
Vascular Tumors
Published in Omar P. Sangueza, Sara Moradi Tuchayi, Parisa Mansoori, Saleha A. Aldawsari, Amir Al-Dabagh, Amany A. Fathaddin, Steven R. Feldman, Dermatopathology Primer of Cutaneous Tumors, 2015
Glomeruloid hemangioma is a vascular proliferation that only occurs in patients affected with the POEMS syndrome. POEMS is an acronym for this syndrome which includes: Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy (M protein), and Skin lesions. Histopathologically, the vascular lesion in patients with POEMS syndrome fall into four categories: microvenular hemangiomas; cherry hemangiomas; multinucleate cell angiohistiocytomas; and glomeruloid hemangiomas. Glomeruloid hemangiomas seem to be fairly specific for POEMS syndrome.
Reactive capillary hemangiomas induced by camrelizumab (SHR-1210), an anti-PD-1 agent
Published in Acta Oncologica, 2019
Yan Teng, Ruifeng Guo, Jianfang Sun, Yiqun Jiang, Yi Liu
Reactive capillary hemangiomas are characterized by rapid capillary proliferation associated with etiologic factors such as trauma, infection and medications. They are a group of benign vascular tumors including papillary endothelial hyperplasia, bacillary angiomatosis, epithelioid hemangioma, glomeruloid hemangioma, eruptive cherry angiomas, pyogenic granuloma and among others [1]. The main concern in these cases is secondary malignant vascular tumors in relation to the known malignancy and/or treatment. However, the clinical and histologic features observed in these cases make the possibility of vascular malignancy highly unlikely.