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Kyrle’s disease effectively treated with oral isotretinoin
Published in Journal of Dermatological Treatment, 2018
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni
Kyrle’s disease (KD) is a primary perforating dermatosis which includes also elastosis perforans serpiginosa, perforating folliculitis and reactive perforating collagenosis. The secondary form of perforating dermatosis is represented by acquired perforating collagenosis (1). The transepidermal elimination of altered skin components (keratins, collagen, or elastin) is the key pathogenetic feature of these disorders (2).