China
Africa
Explore chapters and articles related to this topic
Tissue Grafting Techniques
Published in Vineet Relhan, Vijay Kumar Garg, Sneha Ghunawat, Khushbu Mahajan, Comprehensive Textbook on Vitiligo, 2020
Shaving of the donor and recipient sites before the procedure is important. However, if the recipient area has thick terminal hair, as the transplanted graft starts to grow the hair tends to lift up the graft, which can adversely affect the results. Hence some authors recommend plucking the hair with forceps after administerng anesthesia instead of shaving, as it delays hair growth, thus preventing the graft from being lifted up [12]. Chemical depilation of the hair is another alternative for getting rid of hair prior to the procedure.
The Naked (N) Mutation, Chromosome 15
Published in John P. Sundberg, Handbook of Mouse Mutations with Skin and Hair Abnormalities, 2020
Heterozygotes (N/+) resemble normal Littermates until the first hair coat has grown out. Weight differences between heterozygotes and littermate controls are of no prognostic or diagnostic value. The hair coat of N/+ mice is variable between individuals but is rough and less sleek compared to +/+ controls. Skin folding may be evident in some affected mice. Depilation due to fracture of hair shafts becomes evident around 10 days of age and progresses in the normal cranial-caudal pattern of the hair cycle. Unlike N/N mice, the N/+ mice have vibrissae, other sensory hairs, and hairs of the feet, tail, and genital region, which appear to be normal. The pelage hairs undergo depilation with the exception of scattered individual hairs. With the development of the second hair coat, the skin folding increases, but this feature is lost in subsequent cycles. Differences in the hair coat between pregnant or lactating females and those that are not were initially described1 but were not observed by others.4 Heterozygotes have normal teeth, nails, eyes, and fertility.4
Hairlessness and Metabolic Compensations
Published in Miroslav Holub, Immunology of Nude Mice, 2020
The naked mutant has been known since 1927. Mice homozygous for this dominant gene have almost no hair and nails and most individuals die within 10 days after birth. Heterozygotes (N/ +) have hair breaking off near the root in successive waves proceeding in a cranio-caudal direction, causing patchy depilation. New successive waves of hair growth follow the depilation process. Analysis of hair from black and white naked heterozygotes and normal homozygotes (NS-FR strain) has shown a low tyrosine and glycine content of the “naked” hair (deficiency of the HG proteins), associated with a significantly lower phenylalanine content and an increase of the relative amounts of leucine, lysine, and proline.9 Since the murine hair contains in normal individuals more tyrosine than any animal hair so far investigated9 and the HG proteins are located in the intercellular membrane complex,9 it may well be that some types of hair dysplasias in mice are caused by the HG proteins deficiency and that these types include the nude mouse and its keratins.
An evaluation of the available pharmacotherapy for the treatment of hirsutism
Published in Expert Opinion on Pharmacotherapy, 2023
Leila Asfour, Ahmed Kazmi, Rodney Sinclair
These physical therapies act by either removing the hair shaft from the surface, e.g., shaving and chemical hair removal (depilation) or from above the bulb, e.g. tweezing and waxing (epilation). There are several physical methods for hair removal with light-based hair reduction being the fastest growing modality due to being a noninvasive, efficient, and longer-term treatment. There are a variety of laser devices available and device choice depends on patient characteristics, such as skin type and hair color. Complications such as perifollicular edema, folliculitis, pigmentary changes, and scarring can occur [65]. Total removal of the already androgenized hair follicles will require electrolysis or laser hair removal. It is preferable to begin mechanical approaches after medical therapy has had an opportunity to inhibit hair growth, usually after 6–12 months [66].
Cohort profile – MSK radiation workers: a feasibility study to establish a deceased worker sub-cohort as part of a multicenter medical radiation worker component in the million person study of low-dose radiation health effects
Published in International Journal of Radiation Biology, 2022
Lawrence T. Dauer, Meghan Woods, Daniel Miodownik, Brian Serencsits, Brian Quinn, Michael Bellamy, Craig Yoder, Xiaolin Liang, John D. Boice, Jonine Bernstein
Memorial Sloan Kettering Cancer Center (MSK) consisting of Memorial Hospital (MH) and the Sloan Kettering Institute (SKI) laboratories has a unique history with regard to the use of radiation for the diagnostic and therapeutic treatment of cancer and allied diseases. The initial New York Cancer Hospital (NYCH) was founded in 1884, barely a decade before the seminal burst of discoveries in radiation. Wilhelm Roentgen discovers ‘X-Rays’ in 1895 and a week later makes his famous first X-ray images of the hand of Mrs. Roentgen (Anna Bertha Ludwig) wearing her wedding ring (Pietzch 2018). Henri Becquerel subsequently discovered ‘radioactivity’ and radioactive materials in 1896 and this was quickly followed by the discovery of ‘polonium’ and ‘radium’ by the Curies (Nobel 2018). Immediate attention is given to the application of these rays and materials to the healing arts. Research and use began almost immediately across the world, even in New York where Thomas Edison demonstrated fluoroscopes in 1896 (King 2012). As early as 1902, the NYCH employed X-Rays and X-ray therapies, practices that continue through the present. Also, as early as 1902, several adverse biological effects began to be identified in some medical radiation workers, both short-term (e.g. reddening of the skin, dermatitis, skin ulceration, epilation, eye irritation) and longer-term (e.g. skin cancers, cataracts, and other cancers) (Linet et al. 2010).
Removing the apocrine sweat glands with nasal endoscope assisted suction cutter: a new technique in the treatment of axillary odor
Published in Journal of Dermatological Treatment, 2022
Zhiqiang Wang, Ruike Cao, Quan Liu, Yan Hu, Qi Zhao, Linlin Liu, Ran Du
In terms of postoperative satisfaction, we adopted the subdivision method to evaluate not only the satisfaction of efficacy, but also the major complications. Although this criterion is not necessarily objective, it can still reflect the gap between preoperative psychological expectation and postoperative reality. The satisfaction rate of patients in the endoscopic group for surgical effect, control of sweat secretion and control of scar was higher than that in the trimming group. As for the problem of postoperative hair loss, since part of the underarm hair follicles will be scraped during the surgical operation, the postoperative axillary hair loss should be explained to the patient before the operation, and the consent form should be signed. All women wanted to lose armpit hair, most men didn’t care about hair loss, and a few wanted to keep it. The operation can achieve the double effects of both treatment and depilation; The majority of patients were satisfied with the subjective evaluation of depilation.