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Dentin-Pulp Complex Regeneration
Published in Vincenzo Guarino, Marco Antonio Alvarez-Pérez, Current Advances in Oral and Craniofacial Tissue Engineering, 2020
Amaury Pozos-Guillén, Héctor Flores
In the last two decades, advances in biomaterials and clinical research have made different modalities of treatment to treat the dentin-pulp complex possible, allowing manipulation of reactionary and reparative dentinogenesis. The resolution of infection and the disease process remains the primary goal of any endodontic therapy. A repaired tissue that promotes the resolution of disease and re-establishment of some or all of the original tissue functions should be a desirable goal. The goal of regenerative endodontics is the use of biologic-based procedures to arrest the disease process, preventing its recurrence while favoring the repair or replacement of damaged structures of the dentin-pulp complex.
Effects of Stress on Physiological Conditions in the Oral Cavity
Published in Eli Ilana, Oral Psychophysiology, 2020
Subjects in two of the studies were dental patients undergoing nonsurgical endodontic therapy.14,27 The stressor was the patient’s fear of the upcoming endodontic therapy. Prior to treatment, each subject completed a dental-anxiety questionnaire and supplied a sample of unstimulated pooled saliva. During treatment, patients were instructed to perform different relaxation procedures (e.g., hypnosis, meditation). Another saliva sample and a second dental anxiety questionnaire were obtained after the session was completed. Positive correlations were found between the questionnaire-assessed evaluation of stress and relaxation and the salivary results. The stress-related salivary changes were increased opacity, increased protein, reduced volume, reduced a amylase, and reduced pH. These results were also found when separate salivary gland secretions were used28 and when the technique of relaxation was performed by a patient well trained in deep relaxation through meditation.31
Bacterial Infections of the Oral Cavity
Published in K. Balamurugan, U. Prithika, Pocket Guide to Bacterial Infections, 2019
P. S. Manoharan, Praveen Rajesh
Treatment of a vast majority of endodontic infections include nonsurgical or surgical root canal. The infected root canals are shaped and cleaned until the microorganism load is brought down, and they are filled three dimensionally to achieve a hermetic seal.
Chemotherapy-Induced Oral Complications and Prophylaxis Strategies
Published in Cancer Investigation, 2023
Aleksandra Śledzińska, Paulina Śledzińska, Marek Bebyn, Oskar Komisarek
A program of aggressive oral preventative care appears to reduce the occurrence of all oral complications associated with chemotherapy (159–163). Scaling and root planing, caries treatment, and endodontic therapy should be included in pretreatment oral hygiene routines. A tooth extraction should be considered in cases of severe odontogenic disease. Dental or endodontic treatment should be pursued solely in patients with symptoms consistent with acute periapical infection (29). In patients with periodontal disease, pretherapy dental treatment is often recommended to minimize potential sources of odontogenic infection (27). Prior dental care can reduce the number of oral bacteria and the risk of infection during chemotherapy (164). Invasive manipulation of the soft tissues prior to chemotherapy appears to have no negative influence on the eventual occurrence of fever or bacteremia (165).
Influence of dental education on adoption and integration of technological aids in the delivery of endodontic care by dental practitioners: a survey
Published in Acta Odontologica Scandinavica, 2022
Hanne Q. Christensen, Brita R. Linde, Asgeir Bårdsen, Vilhjalmur H. Vilhjalmsson, Sivakami R. Haug
One advantage of this study was that the survey participants were former students and therefore, we had knowledge of the education they had received. UG education at the University of Bergen (UoB), Norway is based on the European Society of Endodontology (ESE) guidelines [8]. After a five-year long dental education, newly graduated dentists are expected to possess the skills and knowledge to perform a wide range of clinical dental procedures independently in accordance to the ESE guidelines [8]. This survey revealed that around one in three (29%) DPs did or could not refer their patients to an Endodontist. It is therefore important that DPs possess a level of skill where they can perform a wide range of dental procedures independently. Failing to provide appropriate endodontic treatment can result in patients living with pain, chronic periapical disease, or tooth loss with or without expensive replacement therapy.
A small molecule II-6s inhibits Enterococcus faecalis biofilms
Published in Journal of Oral Microbiology, 2021
Xinyi Kuang, Jin Zhang, Xian Peng, Qian Xie, Jiyao Li, Xuedong Zhou, Youfu Luo, Xin Xu
Endodontic diseases are results from inflammation and destruction of pulp and periradicular tissues, primarily initiated by oral biofilms and associated with multiple risk factors [1]. Root canal disinfection, aiming to disrupt biofilms and kill bacteria inside, is critical for successful endodontic treatment [2]. Enterococcus faecalis is the main species commonly isolated from root canals with persistent endodontic infection or post-treatment endodontic diseases [3,4]. Certain virulence factors of E. faecalis, such as collagen-binding protein, gelatinase, enterococcal surface protein and aggregation substance mediate the adherence and biofilm formation on the dentin surface of the root canal system [4–6]. E. faecalis can invade into dentinal tubules, compete with other microorganisms, and survive in the root canals with poor nutrition [3].