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Anti-Hyperglycemic Property Of Medicinal Plants
Published in Amit Baran Sharangi, K. V. Peter, Medicinal Plants, 2023
Karanpreet Singh Bhatia, Arpita Roy, Navneeta Bhardavaj
Eriobotrya japonica, with a common name loquat, is belongs to Rosaceae family. It is natively from cooler hill China to southern China but also quite common in Japan, Himachal, Korea, Potohar, and foot hill region of Pakistan. Sesquiterpene glycoside isolated from dried leaves has shown to possess anti-hyperglycemic effect in alloxan-induced mice models at a dosage of 0.025 and 0.075 g/kg b.w. (Chen et al., 2008). Anti hyperglycemic and anti-hyperlipidemic activity of ethanol extract of E. japonica was observed in AI albino rats with a dosage of 200 mg/kg of body weight (Shafi et al., 2013).
Anti-Obesity Potential of Indian Traditional Medicinal Plants and Their Phytochemicals
Published in Parimelazhagan Thangaraj, Medicinal Plants, 2018
Vellingiri Vadivel, Pichai Venkatalakshmi, Pemaiah Brindha
The administration of black tea polyphenols suppressed postprandial hypertriglyceridemia in a dose-dependent manner in rats, with theaflavin-3,3’-digallate (Figure 7.6) as the most effective pancreatic lipase inhibitor (Kobayashi et al. 2009), whereas other authors point to the thearubigins (Kusano et al. 2008). These extracts are able to prevent increases in body weight and adiposity in mice fed a high-fat diet (Uchiyama et al. 2011). The pancreatic lipase inhibitory and hypotriglyceridemic effects of tea extracts were corroborated by Tanaka et al. (2010), who orally administered mixed fermented tea extracts and Loquat tea extracts to rats with a 10% soybean oil emulsion. Finally, cocoa tea extract (Camellia sinensis var. ptilophylla) is rich in polyphenols with pancreatic lipase inhibitory effect. A single oral administration of this extract produces an inhibition of plasma triglyceride levels in olive oil–loaded ICR mice and triolein-loaded rats (Kurihara et al. 2006).
Fruits, Vegetables and Tubers
Published in Bill Pritchard, Rodomiro Ortiz, Meera Shekar, Routledge Handbook of Food and Nutrition Security, 2016
Almonds (Prunus dulcis), pistachios (Pistacia vera) and macadamia (Macadamia spp.) are warm climate nut crops highly valued by consumers worldwide. For almonds and pistachios the production in low-income countries is relatively insignificant but for macadamia nuts, Malawi, Kenya and Guatemala combine to produce about 20 per cent of the world crop (Anon. 2012). Other subtropical fruits that are relatively minor in production but contribute significantly to the food supply of many countries include loquat (Eriobotrya japonica), tomatillo (Physalis philadelphica), jujuba (Ziziphus jujuba) and cactus pear (Opuntia spp.).
Green synthesis of silver nanoparticles from Eriobotrya japonica extract: a promising approach against cancer cells proliferation, inflammation, allergic disorders and phagocytosis induction
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2021
Majid S. Jabir, Aya A. Hussien, Ghassan M. Sulaiman, Nahi Y. Yaseen, Yaser H. Dewir, Mona S. Alwahibi, Dina A. Soliman, Humaira Rizwana
The loquat, Eriobotrya japonica, is a fruit tree that belongs to the Rosaceae family. This fruit tree is native to southeastern China and southern Japan, and it is also grown in other parts of the world, including the warmest climates. Previous studies showed that E. japonica extract contains many antioxidants and exhibits bioactivity capable of counteracting health issues, including inflammation, diabetes, cancer, bacterial and parasitic infections, pain and allergies. Bioactive compounds, such as phenolics and terpenoids, were isolated and characterized to improve our understanding of the chemical mechanisms underlying the biological activities of loquat extracts. However, poor solubility and bioavailability severely restrict their use [4]. Therefore, scientists used a drug delivery system to improve the bioavailability of the drug and diminish toxicity related to the high doses that are typically required for an optimum response [5].
The Inhibitory Effects of Pentacyclic Triterpenes from Loquat Leaf against Th17 Differentiation
Published in Immunological Investigations, 2020
Xiaoqing Zhou, Huanpeng Chen, Fengjiao Wei, Qingyu Zhao, Qiao Su, Yu Lei, Meng Yin, Xuyan Tian, Zhonghua Liu, Bolan Yu, Chuan Bai, Xixin He, Zhaofeng Huang
Loquat (Eriobotrya japonica (Thunb.) Lindl) is indigenous to southern China. Loquat leaves are widely used as traditional herbal medicines for skin diseases, coughing, nausea, and itching (Saliba et al. 2004). Loquat leaves contain many chemicals, such as volatile oils, triterpenoids, sesquiterpenes, polyphenols, and flavonoids, shown to have diverse biological activities, particularly anti-inflammatory (Huang et al. 2007), cough-relieving, blood-sugar-lowering (Lü et al. 2009), anti-viral (Tommasi et al. 1992), anti-oxidative (Huang et al. 2006), and anti-cancer effects (Ito et al. 2002; Takuhiro et al. 2013). Unlike some other natural plant drugs, loquat leaf also can be used in TCM for some kinds of nephritis therapy. However, it is still uncertain which pathway loquat leaf employed in this application.