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Weight Concerns
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
Lynn, age 74, lost weight on the Whole30® program. In 6 months, she reduced from 183 pounds and a BMI of 29 kg/m2 to 155 pounds with a BMI of 24 kg/m2. Her diet included foods that were anti-inflammatory with mostly protein, veggies, and some fruit. She avoided gluten, sugar, and dairy. Lynn reported feeling 10 years younger, along with reduced knee and joint pain. The Whole30 program encourages eliminating alcohol, sugar, grains, legumes, dairy, and additives from the diet. Recommendations include eating moderate portions of meat, seafood, and eggs; consuming lots of vegetables and some fruit; eating plenty of natural fats; and using herbs, spices, and seasonings rather than salt.
Athletes with Chronic Conditions
Published in Flavia Meyer, Zbigniew Szygula, Boguslaw Wilk, Fluid Balance, Hydration, and Athletic Performance, 2016
Flavia Meyer, Paulo L. Sehl, Emily Haymes
A greater discomfort and perceived exertion of obese individuals while exercising in the heat may indirectly assume that they are at thermoregulatory disadvantage. The obese boys, compared to non-obese, in the study of Sehl et al. (2012) reported a greater heat sensation during the whole 30-min cycling and a greater perceived effort (Borg Scale) in the final 5 min. Obese and non-obese boys presented similar aerobic fitness and heat acclimatization and responded with similar rectal temperature while exercising in the heat. Therefore, a higher perceived effort and fatigue in individuals with greater adiposity levels while exercising in the heat should be considered and may impair motivation and adhesion to training programs.
Constraints on the Hydropathicity and Sequence Composition of HCDR3 are Conserved Across Evolution
Published in Maurizio Zanetti, J. Donald Capra, The Antibodies, 2002
Ivaylo Ivanov, Jason Link, Gregory C. Ippolito, Harry W. Schroeder
The DH gene segment forms the core of HCDR3; thus any limits on the diversity of DH sequence can have a profound influence on the diversity of the antibody repertoire as a whole [30]. It is remarkable, therefore, that in spite of the fact that the D in DH stands for diversity, its sequence composition is actually conserved across evolution.
Atrial fibrillation in the elderly general population: a 30-year follow-up from 70 to 100 years of age
Published in Scandinavian Cardiovascular Journal, 2020
Gustaf Lernfelt, Zacharias Mandalenakis, Björn Hornestam, Bodil Lernfelt, Annika Rosengren, Valter Sundh, Per-Olof Hansson
There is consensus that AF is a risk factor for mortality, even though the causality and the true power of AF compared with associated risk factors have been discussed [33]. Several studies have found an approximate doubling of the mortality risk among patients with AF compared with controls free from AF [6,17–19], consistent with our data from all three cohorts. Irrespective of age, sex, hypertension, diabetes, smoking, BMI and cholesterol levels, AF was associated with a significant over-mortality throughout the observation period, but not to the same extent when AF diagnosed by hospital registers was excluded. In the subgroup analysis of participants from Cohort 1 examined frequently over the whole 30-year period, excluding patient registry data, we found that, the RR for mortality was lower among participants with AF first diagnosed at ECG during a screening procedure than for the whole group of participants with AF. The excess risk of death thus appears to be lower than previously reported among older people with AF diagnosed at out-patient screening examinations. Some more recent studies support our finding in the subgroup analysis, of a lower mortality risk in AF [18,19,34]. Andersson et al. [19] showed no increased mortality rate among men with lone AF at ages of 75 years and above, and mortality rates were consistent with our data at ages between 65 and 74 years. The same study showed a hazard ratio for mortality of 1.4 in women, with AF, at the age of 65 and above.
Upper body sweat mapping provides evidence of relative sweat redistribution towards the periphery following hot-dry heat acclimation
Published in Temperature, 2019
Caroline J. Smith, George Havenith
The present data indicate increases in GSL that are much smaller than increases in total sweating loss captured by the sum of all patches. Post-HA GSL increased 10% at I1, yet SA weighted GSL for the torso and arms together increased 68%. There are two possible causes. The first, described in our earlier studies and confirmed by Morris et al. [38], is that GSL is measured over the whole 30 min period, integrating periods where sweating begins, with periods where sweating rate will have increased markedly. The sample period for the patches occurs during steady state, only capturing the highest sweating rate for that period. In addition, it may suggest that the increase in areas not covered with pads is lower than in the regions measured, but this is difficult to tease out from the first consideration. The biggest surface area not measured is the legs, thus suggesting that RSR on the legs may increase less than the average for the torso and arm regions following HA.
Benzathine penicillin G once-every-3-week prophylaxis for recurrent erysipelas a retrospective study of 132 patients
Published in Journal of Dermatological Treatment, 2018
The primary objective was to determine the efficacy of BPG intramuscularly applied every 3 weeks for the prevention of recurrent erysipelas in our group of patients. For this purpose, comparison of the incidence rates of recurrent erysipelas during prophylaxis and the follow-up period was used. To strengthen the analysis of the study results, all the (3) patients who were lost to the follow-up during the prophylactic period were defined as erysipelas recurrence for the statistical analyzes, as we cannot exclude that these patients had recurrence after the last visit. Conversely, patients who were lost to the follow-up in the postprophylactic period were excluded from the analysis as we also cannot rule out erysipelas recurrence. Patients who did not the finish the whole 30-week prophylactic course due to known reasons were also not included in the efficacy analysis. The processing of the statistical data was performed using the software Statistical Package for the Social Sciences (SPSS), version 24.0 Chicago, IL). The Pearson chi square test with Yates correction or Fisher’s exact test were used for categorical variables and Student’s t-test for continuous variables associated with erysipelas recurrence.