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Nutritional Ergogenic Aids: Introduction, Definitions and Regulatory Issues
Published in Ira Wolinsky, Judy A. Driskell, Nutritional Ergogenic Aids, 2004
Ira Wolinsky, Judy A. Driskell
the benefits of wheat germ oil. Soon its components were isolated and examined separately. Octacosanol appeared to be the primary active compound in wheat germ oil. With the help of Gonzalez-Bravo et al.,3 the analytical procedure for determining octacosanol in plasma was refined. This procedure allowed for higher recovery (94.5-98.7%) and precision (1.8-5.8%) than was ever before permitted.
The protective effect of resveratrol against cyclosporine A-induced oxidative stress and hepatotoxicity
Published in Archives of Physiology and Biochemistry, 2021
Ilknur Bingul, Vakur Olgac, Seldag Bekpinar, Mujdat Uysal
Some investigators have examined the effect of CsA-induced toxicity in several tissues. In these studies, different doses of CsA were used for different periods and the changes in the renal and cardiovascular systems were in focus. Hepatotoxicity induced by CsA remains one of the major clinical problems and limits the use of CSA, especially in liver transplantation. When CsA (7.5–30 mg/kg b.w.) was applied to animals for a period of 7–28 days, increased hepatic lipid peroxides and reduced hepatic GSH levels and antioxidant enzyme activities were found as compared to controls (Kaya et al.2008, Pari and Sivasankari 2008, Yüce et al.2008, Akool 2015, Korolczuk et al.2016). Moreover, CsA application resulted in increases in serum ALT and AST activities together with hepatic histopathological changes (Kaya et al.2008, Pari and Sivasankari 2008, Yüce et al.2008, Akool 2015, Korolczuk et al.2016). Based on these findings, several investigators have investigated the efficiency of some antioxidant compounds such as wheat germ oil, ellagic acid, N-acetylcysteine, melatonin, and taurine against CsA-induced oxidative stress and tissue damage in the liver (Hagar et al.2006, Kaya et al.2008, Pari and Sivasankari 2008, Yüce et al.2008, Kurus et al. 2009, Akool 2015).
Formulation and evaluation of UV protective synbiotic skin care topical formulation
Published in Journal of Cosmetic and Laser Therapy, 2019
The composition used for topical formulation use listed in Table 1. Water in oil emulsion based topical cream was formulated. Measured amount of Stearic acid, cholesterol, lecithin, PEG 1500, wheat germ oil, and tea-tree oil were dissolved in oil phase and heated up to 70ºC. PEG 400, Triethanolamine and glycerin were added in separate beaker and heating up to 70ºC. After heating the water soluble phase was added slowly to the oil phase with continuous mixing till a uniform, smooth emulsion was formed. The mixture was kept aside to cool at 45ºC. Measured amount of probiotic biomass and selenium nanoparticles were added before the finished product was transferred into suitable container. Five different formulations F1,F2, F3, F4, and F5 were prepared with varying concentrations of ingredients up to certain limit to obtain the formulation.