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Influenza
Published in Charles Theisler, Adjuvant Medical Care, 2023
Sambucol, an herbal product that contains extracts of black elderberries (Sambucus nigra L) and raspberries (Rubus idaeus L) has been shown to inhibit the ability of the influenza virus to replicate. In one study, individuals suffering from the flu were given Sambucol. Ninety percent of the individuals receiving Sambucol became symp-tom-free within two to three days. In contrast, those in the placebo group did not recover for at least six days.1 Sambucol one tablespoon (15 mL) by Nature’s Way q.i.d. or lozenge (ViraBLOC) by HerbalScience containing 175 mg of elderberry extract q.i.d. for two days is recommended.2
Hyaluronidase and Gelatinase (MMP-2, MMP-9) Inhibitor Plants
Published in Megh R. Goyal, Durgesh Nandini Chauhan, Assessment of Medicinal Plants for Human Health, 2020
C. Donmez, G. D. Durbilmez, H. El-Seedi, U. Koca-Caliskan
Tannin-rich plants (such as Potentilla erecta (L.) Raeusch, Rubus fruticosus L., Rubus idaeus L., and Quercus robur L.) have an important anti-hyaluronidase effect.57 It has been shown that “Shikimic acid” isolated from Alnus glutinosa (L.) Gaertn. subsp. glutinosa and “ascorbic acid” from Cucumis sativus L. have inhibitory influence on hyaluronidase.2,15 On the other hand, the extracts from Ononis and Solidaginis species inhibit the activity of hyaluronidase enzymes.53Table 15.1 indicates selected plant-based inhibitory hyaluronidase enzyme.
Preclinical Antidepressant-Like Effects of Terpenes, Polyphenolics, and Other Non-Flavonoid Phytochemicals
Published in Scott Mendelson, Herbal Treatment of Major Depression, 2019
Ellagic acid is a polyphenolic compound found in a variety of herbs, including Quercus rubus, Euphorbia antisyphilitica, Quercus alba, Rubus idaeus, and Rubus occidentalis.64 It is also common in a variety of nuts, fruits, and vegetables. It possesses potent neuroprotective effects through its free radical scavenging properties, iron chelation, activation of different cell signaling pathways, and mitigation of mitochondrial dysfunction.65 It also exerts potent anti-inflammatory effects.66
Red raspberry (Rubus ideaus) supplementation mitigates the effects of a high-fat diet on brain and behavior in mice
Published in Nutritional Neuroscience, 2021
Amanda N. Carey, Giulia I. Pintea, Shelby Van Leuven, Kelsea R. Gildawie, Laura Squiccimara, Elizabeth Fine, Abigail Rovnak, Mark Harrington
During the two-week acclimation period, mice were fed standard rodent chow (Connecticut Valley Biological, Southampton, MA, USA) and water ad libitum, after which they were weight-matched and placed on one of four diets (n = 15/diet, Research Diets, Inc, New Brunswick, NJ, USA). At this point, the mice were 10-weeks of age. The diets were: Control Diet (CD, D12450J, 10% calories from fat), CD + 4% freeze-dried red raspberry powder (RB, Rubus idaeus, courtesy of Van Drunen Farms), High-Fat Diet (HFD, D12492, 60% calories from fat), and HFD + 4% RB. CD + RB and HFD + RB were adjusted for macronutrients and fiber to match CD and HFD, respectively. Food intake was assessed at three points during the study: after 1, 2, and 4 months on the diets. There were no differences in the amount of food consumed between the four diet groups at any of the time points (data not shown, all one-way ANOVAs were p > 0.05).
Effect of Raspberry Ketone on Normal, Obese and Health-Compromised Obese Mice: A Preliminary Study
Published in Journal of Dietary Supplements, 2021
Tahir Maqbool Mir, Guoyi Ma, Zulfiqar Ali, Ikhlas A. Khan, Mohammad K. Ashfaq
Fruits of Rubus idaeus L. commonly known as red raspberries are widely available and possess both nutritional and medicinal properties. They possess several essential micronutrients, dietary fibers, and phenolic components, especially raspberry ketone ellagitannins, and anthocyanins. Scientific reports indicate that raspberries are being used in the treatment of diabetes mellitus, cancer, cardiovascular disorders, obesity, and neurodegeneration (Burton-Freeman et al. 2016; Kristo et al. 2016; Noratto et al. 2016). Raspberry ketone is an aromatic compound predominantly found in raspberries and also in other fruits, including black raspberries and kiwifruit (Ulbricht et al. 2011). It is widely used as a fragrance in cosmetics and flavoring agent in foodstuff. Several reports have demonstrated its lipolytic and anti-obesity activities (Morimoto et al. 2005; Leu et al. 2018; Mehanna et al. 2018). In the present study, we induced obesity in mice by feeding them for 10 weeks on a high-fat diet. Increases in body weight and fat storage was noted in accordance with the previously published reports (Morimoto et al. 2005; Mukai et al. 2016). In addition, we explored the possible adverse effects of consumption of RK during normal obese and health compromised obese condition in mice.
Evaluation of Natural Product Compositions for Appetite Suppression
Published in Journal of Dietary Supplements, 2019
Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Tae-Woo Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia
Considering high calorie intake as one of the root causes of obesity, it is not uncommon to find overwhelming choices of dietary supplements marketed for appetite suppression targeting the desperate obese and overweight population. In the current study, we selected pure caffeine, potato skin extract, Cissus quadrangularis aerial parts extract, Garcinia cambogia fruit extract, Crocus sativus bulb extract, and raspberry ketone isolated from mature fruits of Rubus idaeus and compared their efficacy against UP601 and a commercial product (Appetrex) using acute food intake study in rats.