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Common Medicines from Herbs, Minerals and Animal Sources
Published in Mehwish Iqbal, Complementary and Alternative Medicinal Approaches for Enhancing Immunity, 2023
Emblica officinalis, also recognised as Phyllanthus emblica, emblic myrobalan, Indian gooseberry or amla, belongs to the Euphorbiaceae family. Amla is one of the most frequently used medicinal herbs in the traditional system of medicine and has been consumed as a nutritious tonic and medicine for having vitamins and essential amino acids. It is predominantly a major source of minerals and vitamin C contrasted with other citrus fruits. Though all parts of emblic myrobalan are consumed for therapeutic reasons, the fruits are used more extensively as Rasayana, either solely or in blend with other herbs for the management of numerous contagious or non-contagious diseases. The fruits of Emblica officinalis are broadly utilised as antipyretic and anti-inflammatory medicine apart from its typical consumption as a tonic during the season of winter (Ihantola-Vormisto et al., 1997; Srivasuki, 2012).
Role of Diet in Vitiligo
Published in Vineet Relhan, Vijay Kumar Garg, Sneha Ghunawat, Khushbu Mahajan, Comprehensive Textbook on Vitiligo, 2020
Rachita Misri, Khushbu Mahajan
Amla (Phyllanthus emblica) or Indian gooseberry, has antioxidant, anti-inflammatory, antimicrobial, and antiviral properties. It contains vitamin C, tannins, and polyphenols [21]. Colucci et al. have suggested its beneficial efficacy in vitiligo patients. They treated 65 subjects (group A) with one tablet of an oral supplement containing P. emblica (100 mg), vitamin E (10 mg), and carotenoids (4.7 mg) three times a day for 6 months and compared with a control group (group B, 65 patients), which was not treated with antioxidants. Both groups were simultaneously treated with a comparable topical therapy and/or phototherapy. After a 6-month follow-up, a significantly greater number of patients in group A had higher repigmentation, fewer signs of inflammation, and more stable disease, thus suggesting a positive contribution of antioxidant supplementation to other vitiligo treatments [22].
Antihypertensive effects of oriental drugs in human and SHR
Published in H. Saito, Y. Yamori, M. Minami, S.H. Parvez, New Advances in SHR Research –, 2020
Hideaki Higashino, Aritomo Suzuki, Koichiro Komai
It has been also known in China that the leaves of Phyllanthus emblica (P.e.) containing tannins such as glucogallin, gallic acid, ellagic acid, corilagin, terchebin, chebulagic acid and 3,6-digalloyl glucose, and mucic acid, phyllemblic acid and ascorbic acid had diuretic and anabolic actions (ref.A, 1990; ref.F, 1988).
Seed extract of Thai Mucuna pruriens reduced male reproductive damage in rats induced by chronic stress
Published in Pharmaceutical Biology, 2022
Natthapol Lapyuneyong, Nareelak Tangsrisakda, Pannawat Choowong-In, Kowit Chaisiwamongkol, Nongnut Uabundit, Tarinee Sawatpanich, Supatcharee Arun, Alexander Tsang-Hsien Wu, Sitthichai Iamsaard
As documented, many potential plant extracts such as Phyllanthus emblica L. (Phyllanthaceae) leaf, Moringa oleifera Lam. (Moringaceae) leaf and Mucuna pruriens (L.) DC. var. pruriens (Fabaceae) seed were shown to improve the male reproductive damages caused by stress (Prabsattroo et al. 2015; Arun et al. 2018; Ashidi et al. 2019). The seed of Mucuna pruriens (MP), a miracle bean commonly used in Indian traditional medicine, has been reported to have various phytochemical substances (Agbafor and Nwachukwu 2011; Nwaoguikpe et al. 2011; Anosike et al. 2019). In addition, the major substance reported in MP seeds is l-DOPA stimulating GnRH secretion, resulted in increased sex hormones (Vermes et al. 1979; Misra and Wagner 2004; Shukla et al. 2009; Singh et al. 2013; Mutwedu et al. 2019). Moreover, such seeds have been demonstrated to improve the male reproductive dysfunction caused by stress (Ashidi et al. 2019).
Molecular Mechanisms of Cancer Prevention by Gooseberry (Phyllanthus emblica)
Published in Nutrition and Cancer, 2022
Gaurav Kumar, Venkateshwar Madka, Gopal Pathuri, Vishal Ganta, Chinthalapally V. Rao
Many plant extracts, as well as chemicals purified from them, have demonstrated medicinal properties, and have been used to develop numerous traditional herbal therapies demand for which is continuously increasing worldwide. More than 110 thousand plant extracts or purified molecules have been screened for their anticancer efficacy since the start of a National Cancer Institute (NCI) screening program (1). Approximately 25 percent of all medications prescribed in the United States were developed from plants (2), including paclitaxel (commonly known by the tradename Taxol) which is derived from the bark of the Pacific yew tree and may be the most widely used anticancer medication. Similarly, gooseberry (Phyllanthus emblica, Emblica officinalis, or Amla) is an important herbal medicine, commonly used in the Ayurvedic and Unani systems of medicine in South Asia and Arab nations. Different parts of the P. emblica tree have various therapeutic applications in these systems of medicine, including: improving the immune system, treating constipation, reducing stomach acidity, treating stomach ulcers, purifying the blood, and treating diarrhea, dysentery, helminthic infections, diabetes, and cancer (3).
Determination of suppressive effect on human T-cell activation by hispidulin, nepetin, and vanillic acid
Published in Immunopharmacology and Immunotoxicology, 2019
Premrutai Thitilertdecha, Varangkana Tantithavorn, Poonsin Poungpairoj, Nattawat Onlamoon
Flavonoids including hispidulin (4′,5,7-trihydroxy-6-methoxyflavone) and nepetin (3′,4′,5,7-tetrahydroxy-6-methoxyflavone) and a phenolic acid, vanillic acid (4-hydroxy-3-methoxybenzoic acid), are abundantly found in the Thai medicinal plant called Clerodendrum petasites S. Moore [3]. Moreover, the three compounds were reported to be good candidates for skin penetration [4], providing not only oral but also topical routes of drug administration for allergic contact dermatitis. Hispidulin and nepetin are also found in other plant species including Clerodendrum inerme (L.) [5], Clerodendrum indicum (L) Gaertn [6], Salvia plebeian R. Br. (SP) [7], Eupatorium arnottianum Griseb. [8], Santolina insularis (Genn. Ex Fiori) [9], and Artermisia vestita [10]. Vanillic acid is found in several other plants as well, such as Solanum melongena [11], Armillaria mellea [12], Allium sativum L. [13], and Phyllanthus emblica [14]. Because of flavonoids (i.e. hispidulin and nepetin), and phenolic acid (i.e. vanillic acid) are well-known for anti-inflammatory and immunosuppressive potentials, they have been then interested and recently investigated for these activities.