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Fluorescence in Histochemical Reactions
Published in Victoria Vladimirovna Roshchina, Fluorescence of Living Plant Cells for Phytomedicine Preparations, 2020
Victoria Vladimirovna Roshchina
Analogous histochemical analysis for biogenic amines has been carried out in conditions where single cells of pollen and vegetative microspores were grown in high salt concentrations (Roshchina and Yashin 2014). The enhanced fluorescence intensity of Equisetum arvense microspores from sporophytes in histochemical reaction with o-phthalic aldehyde was studied before and after 24 h of germination in Na2SO4 solutions. Secretions from the cell emitted especially brightly at the 1% salt concentration, which shows an increased concentration of histamine released. Dependence of histamine accumulation in seeds of sunflower Helianthus annuus was found by Korobova with coworkers (1988).
Antihypertensive effects of oriental drugs in human and SHR
Published in H. Saito, Y. Yamori, M. Minami, S.H. Parvez, New Advances in SHR Research –, 2020
Hideaki Higashino, Aritomo Suzuki, Koichiro Komai
Helianthus annuus L. (ref.A, 1990; ref.12, 1973). The administration of the ethyl alcohol extract of this plant’s flower disk to the anesthetized cats i.v. caused a dramatic fall of blood pressure, and the effect was assumed to relate to the direct vasodilation.
Unraveling the Complexities of Brazilian Regulations for Medicinal Plants and Herbal Medicinal Products
Published in Luzia Valentina Modolo, Mary Ann Foglio, Brazilian Medicinal Plants, 2019
Ana Cecília Bezerra Carvalho, Melina Cossote Kumoto, João Paulo Silvério Perfeito
It is important to note that, in a similar manner to the international legislation, according to Brazilian law, the same herbal species can be licensed for human use not only in medicines, but also in food, cosmetic and health products, often with effects in a similar way to those approved for drugs and often coexisting on the market with the same dosages (Minghetti et al., 2016). Examples of products obtained from medicinal plants that are regulated in foods are Allium sativum and isoflavones from soybean (Glycine max). Several products of topical use found in Brazilian pharmacies are regulated in Brazil in the area of cosmetics, such as gels and shampoos of Calendula officinalis or Matricaria recutita. There are also products registered in the category of health products, such as vegetable oils, including sunflower (Helianthus annuus) and orange (Citrus aurantium) (Ministério da Saúde, 2016b). Regulation for these other classes of products is more lenient than that required for medicines, causing many products that have lost their registration as medicines to migrate to these other categories.
The use of terpenes and derivatives as a new perspective for cardiovascular disease treatment: a patent review (2008–2018)
Published in Expert Opinion on Therapeutic Patents, 2019
Eric Aian P. Silva, Jéssica S. Carvalho, Adriana G. Guimarães, Rosana de S.S. Barreto, Márcio R.V. Santos, André S. Barreto, Lucindo J. Quintans-Júnior
Ling et al. [27], also in 2012, patented a pharmaceutical composition containing sunflower extracted of Helianthus annuus, with flavonoids, sesquiterpenes (germacranolide (9), heliangolide (10), eudesmane (11)), diterpenes (kaurane) (12), and triterpenes among its constituents. The extract of total terpenes was dissolved in water and/or ethanol (10–95%, v/v). The compound was tested in a hypertensive rat model and in human patients (50, 100, 150, and 200 mg/kg, p.o.) to evaluate its antihypertensive effects. In rats, the compound showed a significant reduction in diastolic and mean BP. In human subjects, it had a rate of effectiveness of 84.6% in the treated group. It not only exhibited great antihypertensive activity but also an improvement of the symptoms with no side effects throughout the treatment.
The effect of chamomile extract obtained in supercritical carbon dioxide conditions on physicochemical and usable properties of pharmaceutical ointments
Published in Pharmaceutical Development and Technology, 2018
Emilia Klimaszewska, Artur Seweryn, Anna Małysa, Małgorzata Zięba, Joanna Lipińska
The study reported here was an attempt to incorporate chamomile extract obtained in supercritical carbon dioxide conditions into the ointment base. A total of five ointment formulations were designed and prepared, differing in the weight ratio of Helianthus Annuus Seed Oil to Chamomilla Recutita extract (5:0, 3.5:1.5, 2.5:2.5, 1.5:3.5 and 0:5). Extract derived from chamomile at its lower concentration contains more biologically active substances than sunflower oil. Consequently, the study was based on weight ratios of chamomile extract to sunflower oil. The formulated ointments had the same quantitative proportions but different qualitative compositions of the hydrophobic phase.
Gamma irradiations induced morphological and biochemical variations in in vitro regenerated ginger (Zingiber officinale rosc.)- an invaluable medicinal spice
Published in International Journal of Radiation Biology, 2021
In contrary to our findings, Hanafy and Akladious (2018) reported significant increase in growth characters (shoot length, root length, fresh and dry weight of shoot and root) of Fenugreek plants irradiated with gamma rays as compared to the control. Several other researches showed morphological variations in plants treated with gamma irradiations. Stenotaphrum secundatum (Li et al. 2010), Helianthus annuus (Jagadeesan et al. 2008), Stylosanthes guianensis (Tan et al. 2009), and Vigna unguiculata (Adekola and Oluleye 2007) all showed changes in morphological characteristics as a result of gamma irradiation.