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Micronutrient Supplementation and Ergogenesis — Vitamins
Published in Luke Bucci, Nutrients as Ergogenic Aids for Sports and Exercise, 2020
Vitamin B12 (cyanocobalamin) supplementation to boys or normal young men did not change half-mile run times,218 grip strength, heart rate recovery, maximal cycle ergometer times,219 VO2max, and other standard strength tests.220 Evidence for a subjective “tonic” effect on patients complaining of “tiredness” was found for hydroxocobalamin (B12) injections in a double-blind crossover study.221 Relation of these finding to athletes may explain the popularity of B12 injections and B12 supplements. Currently, the primary, coenzymatic form of B12, known as cobamamide, Dibencozide™ or 5,6-dimethyl-benzimidazolyl cobamide coenzyme222 has become a popular supplement among weightlifters.223,224 Promotional literature contains a favorable comparison of cobamamide with anabolic steroids as an anabolic agent. What is not generally explained is that the study referred to was performed with 35 young children with growth deficiencies, osteoporosis, or hypoproteinemia.225 Other supporting evidence of B12 as an “anabolic agent” is found in European pharmacopeias, but no studies on athletes are found.
White Matter Hyperintensities (WMH) and clinical outcome after vestibular neuritis
Published in Neurological Research, 2022
Huimin Fan, Jing Feng, Melissa Wills, Liying Wang, Xiaomeng Chen, Xiaokun Geng, Yuchuan Ding
All patients were treated with a gastrodin injection of 600 mg QD and cobamamide tablets for 1 week in combination with vestibular rehabilitation therapy for 6 weeks. This rehabilitative program consists of gaze-stabilizing exercises VOR x1 & x2 (in VORx1, the patient fixes eye on a stationary object while moving the head, whereas in VOR x2, the target moves in the opposite direction to the head, while the eye fixes on the target). Patients received clear written instructions and drawings describing these exercises before discharge.