China
Africa
Explore chapters and articles related to this topic
Cardiovascular Imaging for Early Detection of Coronary Artery Disease
Published in Ayman El-Baz, Jasjit S. Suri, Cardiovascular Imaging and Image Analysis, 2018
Giorgos Papanastasiou, George Markousis-Mavrogenis, Sophie I. Mavrogeni
CMRA can precisely assess the abnormal origin of coronary arteries and the location and dimensions of coronary artery aneurysms. This is facilitated by the larger caliber and the proximal location of the coronary artery aneurysms (CAA). The most important benefit of CMRA is the absence of ionizing radiation, which is of special clinical value for children and women [105, 107] (2, 4). Diseases characterized by ectatic or aneurysmatic coronary arteries are Kawasaki disease, autoimmune vasculitis, and coronary artery ectasia [108–111] (5–8).
Serum irisin and adropin levels may be predictors for coronary artery ectasia
Published in Clinical and Experimental Hypertension, 2022
Bayram Ali Uysal, Mevlut Serdar Kuyumcu
Coronary angiography provides stronger evidence compared to other diagnostic tests to make a diagnosis of coronary artery ectasia (CAE)(1). Considered to be a variation from coronary atherosclerosis, CAE can be typically identified in a coronary artery as a local or extensive expansion by a half diameter larger than that of an adjoining normal artery (1). A study by Markis et al. reported that the two-year mortality rate of CAE; which was diagnosed based on specific anatomical classification, was 15% and that rate was similar to the mortality rate of three-vessel coronary artery stenosis (2). Despite the available studies about the potential roles of diffuse atherosclerosis, endothelial insufficiency, microvascular dysfunction, inflammation, and oxidative stress as potential underlying pathophysiological mechanisms of CAE; the pathophysiology and clinical importance of CAE have not been established, yet (3).
Comparison of systemic immune-inflammation index levels in patients with isolated coronary artery ectasia versus patients with obstructive coronary artery disease and normal coronary angiogram
Published in Scandinavian Journal of Clinical and Laboratory Investigation, 2022
Kerim Esenboğa, Alparslan Kurtul, Yakup Yunus Yamantürk, İrem Müge Akbulut, Durmuş Eralp Tutar
Coronary artery ectasia (CAE), an abnormality of the coronary anatomy, has been defined as localized or diffuse nonobstructive lesions of the epicardial coronary arteries, with a luminal dilatation 1.5 or more times greater than the diameter of the adjacent normal portion of the artery [1]. Isolated CAE is defined as CAE without significant coronary artery stenosis. Isolated CAE is a form of coronary atherosclerosis associated with risks of death and myocardial infarction, equivalent to that of patients with obstructive coronary artery disease (CAD) [2,3]. The underlying precise mechanism responsible for ectasia formation has not been established, however its common co-existence CAD has raised the idea that CAE is a variant of CAD. In the most of cases, it has been attributed to atherosclerosis based on shared common links [4,5]. Inflammation has been reported to be an important component of vascular aneurysm formation [6,7].
Prognostic value of thiol/disulfide homeostasis in symptomatic patients with heart failure
Published in Archives of Physiology and Biochemistry, 2021
Haci Mehmet Caliskan, Serkan Sivri, Erdogan Sokmen, Mustafa Celik, Bilal Ilanbey, Sinan Cemgil Ozbek, Burak Celik
In their study, Grieve and Shah (2003) demonstrated an increase in the levels of oxidative stress markers similar to those found in our study in the setting of HF, and they stated that the increase correlated with the seriousness of myocardial functional disruption and hence the stage of HF. Previous evidence suggested abnormalities in TDH as an important factor in the etiopathogenesis of various disease conditions, such as hypertension (Ates et al. 2016), coronary artery ectasia (Kiziltunc et al. 2016), acute myocardial infarction (Kavakli et al. 2018), diabetes mellitus (Gulpamuk et al. 2018), rheumatoid arthritis (Tetik et al. 2010), cancer (Prabhu et al. 2014), acute kidney failure (Yavuz Otal et al. 2018), chronic asthma (Nar Rukiye 2018), and obstructive sleep apnoea (Dinc et al. 2017). To the best of our knowledge, however, there is no study comparing the dynamics of TDH in HF patients stratified according to LVEF as lower-LVEF, mid-range LVEF, and higher LVEF and demonstrating prognostic cut-off values for in-hospital mortality. Accordingly, ours is the first such study.