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Ebstein’s anomaly of the tricuspid valve
Published in Jana Popelová, Erwin Oechslin, Harald Kaemmerer, Martin G St John Sutton, Pavel Žáček, Congenital Heart Disease in Adults, 2008
Jana Popelová, Erwin Oechslin, Harald Kaemmerer, Martin G St John Sutton, Pavel Žáček
In asymptomatic females with good ventricular function, pregnancy may be well tolerated. There is a certain risk of right ventricular decompensation and arrhythmias in the presence of pregnancy-induced right ventricular volume overload. Atrioventricular nodal reentry tachycardia or atrial flutter may develop. A right-to-left shunt poses the patient at risk for paradoxical embolism. Hypoxemia poses a risk to the fetus. Pregnancy is contraindicated in significant cyanosis, serious arrhythmia and right-heart failure.
Cardiac sarcoidosis – an expert review for the chest physician
Published in Expert Review of Respiratory Medicine, 2019
Jamie S. Y. Ho, Edwin R. Chilvers, Muhunthan Thillai
Historically, atrial arrhythmias were not considered to be a primary manifestation of CS [27]. However, recent studies suggest they are more common than previously thought [28] with a prevalence of between 5% and 30% [29]. One retrospective study showed that supraventricular arrhythmias were present in 32% of patients with CS, and the majority (95%) were symptomatic [30]. Atrial fibrillation was the most common atrial dysrhythmia (18%), followed by atrial tachycardia, atrial flutter and atrioventricular nodal reentry tachycardia. Left atrial enlargement was found to be the only variable investigated which was associated with supraventricular arrhythmias [30]. One autopsy study found that although 15–17% of patients with CS had atrial arrhythmias, only 2 of 15 patients revealed granulomas in the atrial wall, concluding that those atrial arrhythmias may be more likely secondary to ventricular dysfunction and atrial dilatation than direct atrial sarcoidosis [7]. However, there is evidence that the left atrial volume increase is not associated with increased filling pressure or diastolic dysfunction, thus supporting a primary atrial infiltration hypothesis. However, prospective studies on larger cohorts are needed to confirm this finding [29].
A systematic review on efficacy, safety, and treatment-durability of low-dose rituximab for the treatment of Pemphigus: special focus on COVID-19 pandemic concerns
Published in Immunopharmacology and Immunotoxicology, 2021
Soheil Tavakolpour, Zeinab Aryanian, Farnoosh Seirafianpour, Milad Dodangeh, Ifa Etesami, Maryam Daneshpazhooh, Kamran Balighi, Hamidreza Mahmoudi, Azadeh Goodarzi
In the study that used a single course of two infusions of 500 mg of rituximab was administered with an interval of 2 weeks [16], in four patients (26%) early mild adverse effects were seen; two of them involve influenza-like symptoms, one of them had a mild herpes zoster and the fourth one who had arrhythmias in his medical history, shown an atrioventricular nodal reentry tachycardia with chest pain. At week 29, a serious adverse event seen followed by mycophenolate mofetil 2 g daily in a patient; sepsis due to neutropenia. After stopping mycophenolate mofetil the patient recovered from the neutropenia and his disease improved.
Burden of arrhythmia and silent ischemia in heart transplant patients with cardiac allograft vasculopathy
Published in Scandinavian Cardiovascular Journal, 2021
Katrine Berg, Kamillla Pernille Bjerre, Tor Skibsted Clemmensen, Brian Bridal Løgstrup, Henning Mølgaard, Steen Hvitfeldt Poulsen, Hans Eiskjær
No difference in the occurrence of premature atrial complexes (PAC) was observed. An insignificant tendency for more SVT occurrence was observed in the CAV 2 + 3 group (CAV 0: 39% CAV 1: 27% CAV 2 + 3: 67%, p = .13). 19% of SVT episodes were characterized as atrial fibrillation (AF), 10% as atrial flutter (AFL), the remaining were characterized as atrioventricular reentry tachycardia, atrioventricular nodal reentry tachycardia, or focal atrial tachycardia.