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Wound Healing, Ulcers, and Scars
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Saloni Shah, Christian Albornoz, Sherry Yang
Final comment: Arterial insufficiency leads to decreased arterial blood flow. If not diagnosed, the dermatologic manifestation may occur. Management of these ulcers includes proper wound care as well as addressing the underlying contributing mechanisms.
Vascular
Published in Ian Mann, Alastair Noyce, The Finalist’s Guide to Passing the OSCE, 2021
Ask the patient to sit up and swing their legs over the edge of the bed. Look at the patient’s leg for 2-3 minutes. Buerger’s test is positive if the patient’s legs turn a waxy, cadaveric white colour on elevation with emptying, or ‘guttering’ of the superficial veins, followed by a reactive hyperaemia on dependency. This implies significant arterial insufficiency.
Wound healing and ulcers
Published in Rashmi Sarkar, Anupam Das, Sumit Sethi, Concise Dermatology, 2021
Arterial insufficiency can be acute or chronic. Acute limb ischemia results from an embolic phenomenon and results in gangrene and acute ulceration. Progressive atherosclerosis is the commonest aetiology resulting in chronic ischemia. It affects large vessels. Other diseases that can cause ischemic ulceration are thromboangiitis obliterans, vasculitis, livedoid vasculopathy, and cryoglobulinemia.
Contribution of ankle-brachial index measurement in screening for arteriopathy obliterans of the lower limbs in type 2 diabetics
Published in Journal of Endocrinology, Metabolism and Diabetes of South Africa, 2022
Sitraka Angelo Raharinavalona, Rija Eric Raherison, Thierry Razanamparany, Dally Rasoaniana, Radonirina Lazasoa Andrianasolo, Andrinirina Dave Patrick Rakotomalala
Atherosclerosis has become the leading cause of death among diabetics. Indeed, diabetes is an important risk factor for coronary atherosclerosis and peripheral arterial disease, independent of other cardiovascular risk factors. In addition, atherosclerosis in diabetics is more diffuse, more severe and manifests at an earlier age by about 10 years.1 One of the components of the ‘diabetic foot’ with neuropathy and infection, obliterating arteriopathy of the lower limbs (OALL), is the main factor in major amputation in diabetics.2 Amputations are linked to arterial insufficiency in 92% of cases, with diabetes being the cause in 50% of cases. It is estimated that the number of amputees for lower limb arterial insufficiency will increase by 50% by 2030 and 100% by 2050.3 Particularly in Africa, the diabetic foot is responsible for great morbidity and mortality. Its healing is significantly influenced by the presence of arteriopathy.4 Therefore, OALL must be sought and detected systematically and early in diabetics in the same way as other degenerative complications.
Rhodotorula minuta as a hypersensitivity pneumonitis causative agent in contaminated continuous positive airway pressure device: A case report
Published in Canadian Journal of Respiratory, Critical Care, and Sleep Medicine, 2022
Florence Côté, Marie-Eve Bédard
A 69-year-old ex-smoker was admitted to the hospital with fever, dyspnea and cough. He was previously known for diastolic heart failure, atrial fibrillation under anticoagulant, hypertension, dyslipidemia, type II diabetes, possible asthma with obstructive pattern on pulmonary function testing in 2009 and rheumatoid polyarthritis treated with Prednisone 10 mg per day. He had had a CPAP for an obstructive sleep apnea since 2007. He was also known for pleural plaques from previous asbestos exposure and a chronic unilateral pleural effusion. He had been hospitalized two months earlier for osteomyelitis of his fifth left toe complicated by Streptococcus hemolyticus lutetiensis bacteremia; he had been successfully treated with 42 days of antibiotics. His toe was considered healed on the day of his admission. Angiography later proved arterial insufficiency.
Pembrolizumab related Guillain barre syndrome, a rare presentation in a patient with a history of lupus and bladder cancer
Published in Journal of Community Hospital Internal Medicine Perspectives, 2021
Vikram Sangani, Mytri Pokal, Mamtha Balla, Ganesh Prasad Merugu, Sreedhar Adapa, Srikanth Naramala, Venu Madhav Konala
Hospital course: Due to lower back pain and weakness in the lower extremities, he underwent computed tomography (CT) of the cervical, thoracic and lumbar spine which revealed multiple bony sclerotic lesions consistent with metastasis and multifocal lymphadenopathy. The patient received 10 mg of dexamethasone initially. Magnetic resonance imaging (MRI) was not done due to pacemaker placement 2 months ago. Neurosurgery recommended no indication for surgical decompression. With a history of Peripheral arterial disease and associated chronic skin discoloration in lower extremities, arterial ultrasound was ordered, which showed occlusion of left distal superficial femoral and left dorsalis pedis arteries with extensive plaque formation bilaterally. Vascular surgery was consulted who reviewed the ankle-brachial pressure index (ABPI), which is more specific for lower extremity ischemia, which was negative. They concluded that the weakness is unrelated to arterial insufficiency.