Posterior parahippocampal gyrus

Overview of Alzheimer’s disease in Down syndrome

Published in Vee P. Prasher, Down Syndrome and Alzheimer’s Disease, 2018

Robert J. Pary, Gautam Rajendran, Andrea Stonecipher

Another brain-imaging approach to determining the natural history of dementia in DS is to measure brain areas and memory function in prodromal phases of DAD.48 Krasuski and colleagues found that the volumes of the right and left amygdala, hippocampus and posterior parahippocampal gyrus were positively associated with age in adults with DS without dementia.48 Furthermore, the amygdala and hippocampal volumes correlated with memory scores.

A case study of topographical disorientation: behavioural intervention for achieving independent navigation

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Journal Information

Published in Neuropsychological Rehabilitation, 2018

Josée Rivest, Eva Svoboda, Jeff McCarthy, Morris Moscovitch

Anatomically, the bilateral medial occipital and posterior parahippocampal cortices, the right hippocampus, and the right inferotemporal region have been shown to be involved in route learning (Barrash, Damasio, Adolphs, & Tranel, 2000). Perception and learning of multiple topographical scenes appear to be correlated with activation in the bilateral medial occipitotemporal cortices and right inferotemporal cortex. Formation of integrated representations of places and their spatial relationships seems to be related to the bilateral posterior parahippocampal gyri, and the right hippocampus (e.g., Aguirre & D’Esposito, 1999; Alsaadi, Binder, Lazar, Doorani, & Mohr, 2000; Barrash, 1998; Maguire, Frackowiak, & Frith, 1997; Martinaud et al., 2012).

Posterior parahippocampal gyrus

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Overview of Alzheimer’s disease in Down syndrome

A case study of topographical disorientation: behavioural intervention for achieving independent navigation