Multifocal fibrosclerosis

Goitre

Published in K. Gupta, P. Carmichael, A. Zumla, 100 Short Cases for the MRCP, 2020

These include: Dyshormonogenetic goitre: e.g. organification/coupling/ dehalogenase/iodine trap defects.Drug-induced: e.g. anti-thyroid drugs, sulphonylureas, lithium.Simple non-toxic goitre: (aetiology unknown, though often accounts for the majority in a non-endemic region).Autoimmune thyroiditis: e.g. Hashimoto's thyroiditis.Reidel's thyroiditis: (very rare; part of the group of conditions referred to as multifocal fibrosclerosis, which includes mediastinal fibrosis, retroperitoneal fibrosis, sclerosing cholangitis and orbital pseudotumour). Subacute thyroiditis (de Quervain's):secondary to a presumed viral thyroiditis.

Refractory cerebrospinal fluid leak following posterior fossa surgery secondary to superior vena cava obstruction: a case report

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Journal Information

Published in British Journal of Neurosurgery, 2022

Kristy Kehoe, Manjunath Prasad, Atul Vats

Neurological sequelae of SVCS include headache, altered mental status and more rarely, cerebral oedema.1,2 The link between venous congestion and raised intracranial pressure has been well documented. One 2009 case report describes a patient presenting with recurrent spontaneous CSF rhinorrhoea who was later found to have evidence of SVC obstruction second to idiopathic multifocal fibrosclerosis.3 A number of studies describe hydrocephalus associated with SVC obstruction, typically in paediatric patients following surgery for transposition of the great vessels.4,5

Multifocal fibrosclerosis

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Goitre

Refractory cerebrospinal fluid leak following posterior fossa surgery secondary to superior vena cava obstruction: a case report