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Nanoencapsulation of Iron for Nutraceuticals
Published in Bhupinder Singh, Minna Hakkarainen, Kamalinder K. Singh, NanoNutraceuticals, 2019
Naveen Shivanna, Hemanth Kumar Kandikattu, Rakesh Kumar Sharma, Teenu Sharma, Farhath Khanum
Trauma is one of the most important pathologic causes for blood loss, besides several GI-related pathological disorders, such as GI carcinomas, ulcers, inflammatory diseases, and hemorrhoids. Aspirin intake further aggravates such loss of blood by GI tract. Indeed, demand for iron will increase in case of hemorrhages due to the loss of RBCs or blood. Celiac disease (sprue) is one of the diseases that could impair iron absorption. Therefore, adults identified with iron deficiency go for endoscopic procedures for identification of the source of bleeding. This type of anemia will be characterized by decreased amount of hemoglobin resulting in less magnitude of mean corpuscular hemoglobin (MCH) owing to reduced size of RBCs. This condition is termed as hypochromic microcytic anemia. Total serum iron also gets diminished, whereas serum iron binding capacity will rather increase, with low transferrin saturation percent (5–10%). In individuals from high altitude regions, serum soluble transferrin receptors will be more expressed (Andrews, 1999; Clark, 2009).
Acute and two-week inhalation toxicity studies in rats for Polyalphaolefin (PAO) fluid
Published in Journal of Toxicology and Environmental Health, Part A, 2021
David R. Mattie, Matthew D. Wegner, Brian A. Wong, R. Arden James, Karen L. Mumy, Shawn M. McInturf, Barry J. Marcel, Teresa R. Sterner
Blood samples were only taken from the 2-week recovery cohort animals at the time of necropsy to look for possible delayed effects. Samples of whole blood with anticoagulant were evaluated using a blood analyzer (Hemavet 950, Drew Scientific, Dallas, TX) for the following metrics: neutrophils, lymphocytes, monocytes, eosinophils, basophils, red blood cells, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red blood cell distribution width, platelets, and mean platelet volume. Plasma samples were examined using a chemistry analyzer (Vet Test 8008 and Vet Lyte, IDEXX Laboratories, Westbrook, ME) for albumin, alkaline phosphatase, alanine transaminase, aspartate aminotransferase, blood urea nitrogen, cholesterol, creatine kinase, creatinine, globulins, glucose, total bilirubin, total protein, triglycerides, sodium, potassium, and chloride.
Haematological and histological changes in fish Heteropneustes fossilis exposed to pesticides from industrial waste water
Published in Human and Ecological Risk Assessment: An International Journal, 2019
Pradip Kumar Maurya, D. S. Malik, Krishna Kumar Yadav, Neha Gupta, Sandeep Kumar
The hematologic indices such as MCH, MCV, and MCHC indicated noticeable variation in H. fossilis exposed to different concentrations of industrial effluent contaminated wastewater (Tables 7–8 and Figures 8 and 11–13). The mean corpuscular hemoglobin (MCH) showed an increase on the 1st day at concentration 10% (30.252 pg) and mean corpuscular volume (MCV) showed an increase on the 1st day at concentration 10% (102.928 fl) compared to the control, after that a considerable decrease was noticed for various concentrations and days of treatment. In both MCH and MCV, the analysis showed highly decline in day wise and concentration wise. The tests for both MCH and MCV showed significant differences between days wise. Similarly, significant variation was observed between various concentrations except between 10 and 50% shown in (Tables 6 and 7, Figures 8 and 10). The mean corpuscular hemoglobin concentration (MCHC) showed a decreasing trend from the control value with the increase in concentration of the pollutant (Table 8 and Figure 12).
Biochemical and hematological effects of lead exposure in Iranian battery workers
Published in International Journal of Occupational Safety and Ergonomics, 2023
Fatemeh Kargar-Shouroki, Hamidreza Mehri, Faeze Sepahi-Zoeram
Blood samples (5 ml) were collected in Complete Blood Count (CBC) tubes (Becton Dickinson, Franklin Lakes, NJ) containing ethylenediamine tetraacetic acid (EDTA) as the anticoagulant, placed in a flask containing dry ice bags at 4 °C and transported to the laboratory to analyze hematological parameters. The complete blood cell count including white blood cells (WBCs), red blood cells (RBCs), hemoglobin (Hb), hematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW) and platelet count (PLT) was counted by a hematology cell counter (Nihon Kohden, Japan).