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A Bayesian Monotonic Non-parametric Dose-Response Model
Published in Human and Ecological Risk Assessment: An International Journal, 2021
Faten S. Alamri, Edward L. Boone, David J. Edwards
Recall that one of the constraints for the AM-Spline is that and for decreasing percent to control data. In order to achieve this constraint the Stick-Breaking prior is chosen as it is a Dirichlet process (DP) that has the same constraints as our model. Let then where the αj are parameters of the Dirichlet distribution. The Dirichlet Process has several sampling methods such as: pólya urn, Chinese Restaurant Process, Hierarchical Dirichlet Process, Indian Buffet Process and the Stick Breaking process (Frigyik et al. 2010). For more about Stick breaking process see Müller et al. (2015).