Thallium-201

Thallium-201

Thallium-201 is a radiometal that is produced through cyclotron and has a half-life of 73 hours. It has principal gamma emissions at 135 keV (2.6%) and 167 keV (10%), but for imaging purposes, the low energy x-ray emissions at 69 keV (27%), 71 keV (46%), and 80.2 keV (10%) from the decay product 201Hg are used. Thallium-201 is used for imaging coronary artery disease and other heart conditions.From: Handbook of Nuclear Medicine and Molecular Imaging for Physicists [2022], Image Processing with MATLAB [2019]

A Survey of Medical Imaging Systems

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Published in Robert B. Northrop, Non-Invasive Instrumentation and Measurement in Medical Diagnosis, 2017

Robert B. Northrop

Another radioisotope used in SPECT bone imaging and cardiac studies is Thallium-201. 201Tl is produced with a cyclotron from 203Tl. 201Tl decays by electron capture to Mercury-201, a stable isotope. 201Tl emits gamma photons with energies of 135 and 167 keV. It is a good thing if little is used; Tl and Hg salts are poisons.

Non-invasive imaging techniques to assess myocardial perfusion

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Published in Expert Review of Medical Devices, 2020

Olivier Villemain, Jérôme Baranger, Zakaria Jalal, Christopher Lam, Jérémie Calais, Mathieu Pernot, Barbara Cifra, Mark K. Friedberg, Luc Mertens

Different SPECT and PET radiotracers can be used for NMPI each with its advantages and disadvantages [20]. NMPI radiotracers show a linear relationship between peak stress MBF and myocardial tracer concentration uptake. The commonly used MPI SPECT tracers are Thallium-201 (201Tl), Technetium-99 m Sestamibi (99 mTc-MIBI) and Technetium-99 m-Tetrofosmin. The main MPI PET tracers are 13 N-ammonia (13 N-NH3), Oxygen-15-water (15O-H2O), rubidium-82 (82Rb) and Fluorine-18 (18 F)-flurpiridaz (Figure 4).

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A Survey of Medical Imaging Systems

Non-invasive imaging techniques to assess myocardial perfusion