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NanotechnologyThe Hope for New Generation and Its Therapeutic Applications
Published in Pradipta Ranjan Rauta, Yugal Kishore Mohanta, Debasis Nayak, Nanotechnology in Biology and Medicine, 2019
Dnyaneshwar Rathod, Avinash Kharat, Varsha Wankhade, Mahendra Rai
For many decades, silver compounds have been widely used for sanitation and in injury healing purposes because of their promising antibacterial activity (Rigo et al., 2013). Considering the advantages of silver, a number of products have been developed in order to cure chronic wounds. The combination of silver nanoparticles with wound-dressing bands enhanced the healing in superficial burn wounds but not too much variance was observed in deep burn wounds (Chen et al., 2013). Other authors summarized that the silver nanoparticles were found to be a catalyst agent with the wound-dressing, band which increased its efficacy. Moreover, Huang et al. (2007) noticed that silver nanoparticles impregnated in wound-dressing band significantly decreased the time required for wound healing when compared with silver sulfadiazine, and with no side effects. Nanotechnology provides great opportunities to develop wound-healing treatments. The nanoparticles open the new era for the development of novel materials that can be used in advanced medical technology. The silver nanoparticle shows significant biological properties, like anti-inflammatory, antiviral, and antibacterial activities with minimum bacterial resistance (Gunasekaran et al., 2012).
Mg-Ag-Based Alloy Systems for Biomedical Applications
Published in Yufeng Zheng, Magnesium Alloys as Degradable Biomaterials, 2015
Silver (Ag), with a density of 10.49 g/cm3 at room temperature, is a precious metal chemical element. Silver is quite ductile and malleable. Silver compounds are used in photography, batteries, bactericide, catalysts, medicines, lubrication, cloud seeding, window coatings, mirrors, flower preservative, electroplating, and sanitation of swimming pools and hot tubs. Silver and silver alloys are used in jewelry, silverware, electronic components, solders, brazing alloys, bactericide, dental amalgams, bearings, coinage, heat sink, ignition-proofing, superconductors, and hydrogen storage (Wang et al. 2002; Drake 2005; Li et al. 2005; Singh et al. 2008; Zeng et al. 2010; Y. Wu et al. 2012).
Commentary
Published in Debasis Bagchi, Manashi Bagchi, Metal Toxicology Handbook, 2020
Debasis Bagchi, Manashi Bagchi
Silver, in its metallic form, induce minimal or no health risks. In fact, healthy skin provides a protective barrier against the absorption of silver.10 However, exposure to soluble silver compounds demonstrated to exert toxic manifestations as demonstrated by hepatic, renal and intestinal tract injuries, neurological, nephrotoxicity, ocular and dermal irritation, hematological injury, and adverse modulation in the blood cells.10 Silver may cause genotoxicity, but its carcinogenic potential hasn’t yet been proven.10
A new silver 1D-coordination polymer with bridging 2-aminopyrimidine, synthesis, characterization and antibacterial activity
Published in Journal of Coordination Chemistry, 2021
Ghasem Ahadiat, Masoumeh Tabatabaee, Khodayar Gholivand, Karim Zare, Michal Dušek
Many silver compounds have antimicrobial activities [21]. One of the most popular silver drugs is silver sulfadiazine (SSD or AgSD) used in wound therapy [22]. Some silver(I) complexes exhibit greater cytotoxic activity than cis-platin for cancer treatment with relatively low toxicity to normal human cells. Ag(I) complexes show selectivity toward various types of tumor cells, dependent on the type of ligand linked to silver(I). This dependency is probably connected with the stability of the complexes and the hydrophilicity-lipophilicity of the complexes formed by the ligands [23].
Investigation of structural and biological properties of N-heterocyclic carbene silver(I) and palladium(II) complexes
Published in Journal of Coordination Chemistry, 2018
N-Heterocyclic carbene (NHC) complexes are important in inorganic and bio-inorganic chemistry. Recently, the importance of their transition metal complexes is increasing due to their biology, pharmacology and catalysis properties [1–5]. Especially Pd and Pt complexes are important in the catalysis and polymerizations [6, 7]. Due to the linear structure, Cu, Ag, and Au complexes are important in the anticancer research [8]. It is known that silver compounds have antimicrobial, antifungal, antibacterial, and anticancer properties [9–12].