Intrinsic activity

Intrinsic activity refers to the inherent ability of a catalyst to catalyze a reaction, which is determined by its electronic structure, charge density, and charge/electron/mass transfer capability. Increasing the proportion and intrinsic activity of active sites of a catalyst is crucial for enhancing its catalytic performance.From: 21st Century Nanoscience – A Handbook [2020], Nanoscale hetero-interfaces for electrocatalytic and photocatalytic water splitting [2022]

Nanoscale Alloys and Intermetallics: Recent Progresses in Catalysis

View Chapter

Purchase Book

Published in Klaus D. Sattler, 21st Century Nanoscience – A Handbook, 2020

Arnab Samanta, Subhra Jana

It is essential to increase the proportion and intrinsic activity of active sites of a catalyst. Moreover, tuning of size, shape and composition at the atomic and nanoscale dimensions is a key aspect to introduce a major effect on their activity.

Regulatory considerations in biosimilars: Asia pacific regions

View Article

Journal Information

Published in Preparative Biochemistry & Biotechnology, 2021

Anurag S. Rathore, Ankita Bhargava

Clinical Documentation: An applicant has to submit comparative clinical studies. In some cases, comparative PK/PD studies between the biosimilar product and the RBP may be sufficient to demonstrate clinical comparability if following conditions are met:The PK profile of the RBP is well characterized.There is sufficient knowledge of the PD properties of the RBP, including the binding to its target receptor(s) and intrinsic activity.The relationship between dose/exposure and response/efficacy of the RBP is sufficiently characterized.At least one PD marker is accepted as a surrogate marker for efficacy, and the relationship between dose/exposure to the product and this surrogate marker is well known.

Intrinsic activity

Explore chapters and articles related to this topic

Nanoscale Alloys and Intermetallics: Recent Progresses in Catalysis

Regulatory considerations in biosimilars: Asia pacific regions