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Fucoidan
Published in Se-Kwon Kim, Marine Biochemistry, 2023
Ellya Sinurat, Dina Fransiska, Nurhayati, Hari Eko Irianto
The inflammatory breach in the skin or mucus membrane that lines the stomach or duodenum is an ulcer. The most frequent upper gastrointestinal (GI) tract condition is peptic ulcer. Ulceration occurs when the natural equilibrium is disrupted by either increased aggression or decreased mucosal resilience (Gregory et al., 2009). The acid peptic disease includes hyperacidity, gastroesophageal reflux, and stress-induced mucosal erosions. Peptic ulcers are caused by a localized loss of gastric and duodenal mucosa. Peptic ulcer disease is becoming more common throughout the population due to people’s bad eating habits. People who take non-steroidal anti inflammatory drugs and smokers and alcoholics have a higher infection rate. Although western medications are efficient, they have side effects, such as diarrhea, dizziness, muscle soreness, and headache, limiting their use. Herbal medicines are effective in clinical and experimental research (Anbarasan et al., 2019; Bujanda, 2000).
Herbal Therapies
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
H. Shahrul, M. L. Tan, A. H. Auni, S. R. Nur, S. M. N. Nurul
Another condition which is treated with herbs is peptic ulcer, it is a major GI disorder that occurs due to an imbalance in mucosal offensive (gastric acid secretion) and defensive (gastric mucosal integrity) factors (Umukoro and Ashorobi, 2006). Among the factors causing peptic ulcer are Helicobacter pylori infection, smoking, drinking alcohol, and chronic ingestion of drugs (Zhang et al., 2010).
Clinical Use of Pulsed Electromagnetic Fields (PEMFs)
Published in Marko S. Markov, James T. Ryaby, Erik I. Waldorff, Pulsed Electromagnetic Fields for Clinical Applications, 2020
Treatment of duodenal ulcers with a 50-Hz, 20- to 25-mT (200- to 250-G) magnetic field applied for 1 min to acupuncture points, commonly used for general adaptation and more specifically for gastrointestinal function, was compared to standard antiulcer medication and the combination of medication and acupuncture point stimulation (Kravtsova et al., 1994). Time to pain relief, reduction of dyspepsia symptoms, and ulcer healing were compared. Pain and dyspepsia were best controlled in the sole therapy group in 2.75 days and 3.08 days, respectively. Ulcer healing took 18.25 days, 8 days less than in the medication-only group (26.6 days). Combining PEMF and drug therapy resulted in pain control in 8.61 days; dyspepsia was relieved in 6.05 days, and also healing occurred in 19 days after the start of the treatment. So, compared to other studies, where medication plus active therapy was better, in this study, adding medication appears to delay improvement.
Validating a wheelchair in-seat activity tracker
Published in Assistive Technology, 2022
Nauman Ahad, Sharon E. Sonenblum, Mark A. Davenport, Stephen Sprigle
Wheelchair users, especially users with spinal cord injuries, experience limited sensory cues to move within their chairs. This leads to extended periods of stationary sitting (Sonenblum et al., 2016) which causes extensive loading of body tissues, particularly around the ischial tuberosities and sacrum and coccyx. Increased loading of tissues, both in magnitude and duration, can hinder blood and oxygen supply to tissues which can cause pressure ulcers. About 46% of 300,000 people with spinal cord injuries in the United States experience pressure ulcers (N.S.C.I.S.C, 2015). After sustaining spinal cord injuries, more than 20% require costly surgeries to manage these ulcers (Saunders et al., 2012). The recurrence rate for pressure ulcers can be up to 79% which further adds to healthcare costs (Bates-Jensen et al., 2009). These pressure ulcers can become infected, leading to life-threatening complications such as sepsis – such complications are associated with mortality rates of 48%.(N.S.C.I.S.C, 2015).
A novel fuzzy expert system design to assist with peptic ulcer disease diagnosis
Published in Cogent Engineering, 2021
Saeedreza Arab, Kianaz Rezaee, Ghazaleh Moghaddam
A peptic ulcer is one of the essential diagnosis concerns (Lanas & Chan, 2017). Peptic ulcer illness involving duodenal and gastric ulcer is the most common gastrointestinal disorderliness (Laine & Peterson, 1994; Umashanker & Shruti, 2011). A peptic ulcer is a lesion in the lining mucosa of the digestive tract, typically in the stomach or duodenum. It is caused by the digestive action of pepsin and stomach acid. Different factors such as Helicobacter pylori can cause gastrointestinal ulcers (Fashner & Gitu, 2015). Helicobacter pylori is a type of bacteria that can cause stomach infections and inflammation (Malfertheiner et al., 2017). Gastroenterologists decide based on diagnostic, therapeutic and monitoring problems (Quinlan, 1986). In health-care procedures diagnostic part is started by evaluating clinical data from physical examination and patient history. The diagnostic hypotheses given at this level are refined and ultimately confirmed with more information in the following part. Disease classes are defined as erosive gastritis, gastro-oesophagealreflux, chronic antral gastritis, and peptic ulcer (Umashanker & Shruti, 2011). Frequent use of drugs, smoking, alcohol, radiation therapy, and gastric cancer are among other causes of ulcers (Ramakrishnan & Salinas, 2007). Furthermore, it is important to note that suggested pharmaceutical products for gastric ulcers are not occasionally effective. To the best of our knowledge, numerous unfavorable symptoms are reported as a result of using them. Nowadays, the focus on herbal studies represents a high potential application of medicinal herbs in this field (Pena-Reyes & Sipper, 1999). It is valuable to diagnose disease according to the symptoms at an early stage to treat by either chemical or herbal medications.