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Nonlinear tissue processing in ophthalmic surgery
Published in Pablo Artal, Handbook of Visual Optics, 2017
Today these lasers have developed from a pure flap-maker for LASIK surgery [Rat 01] to a multiple tool for corneal surgery such as the generation of intrastromal pockets for corneal inlays and corneal rings, performing keratoplasties and arcuate incisions [Kym 12]. With the development of the SMILE® procedure (small incision lenticule extraction), the fs laser has even started to challenge the ArF-excimer laser technology since it uses only one femtosecond laser to complete the refractive surgery [Ang 12, Gan 14].
Quantification for biomechanical properties of human cornea by using acoustic radiation force optical coherence elastography
Published in Journal of Modern Optics, 2022
Yanzhi Zhao, Yongbo Wang, Yueyuan Xu, Yunjiang Zhang, Hongwei Yang, Xiao Han, Yirui Zhu, Yubao Zhang, Guofu Huang
The cornea, lying in front of the iris and pupil, is a totally transparent avascular connective tissue which provides three-fourths of the total refractive power of the human eye along with the tear film on the ocular surface [1,2]. Most refractive errors, such as myopia, hyperopia and astigmatism can be attributed to the altered biomechanical properties of the cornea [3]. Corneal refractive surgeries such as laser-assisted in-situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) have gained considerable popularity in recent years, offering a long-term solution to refractive errors. However, these surgeries are always accompanied by the alteration of cornea elasticity between pre- and post-operation, and there is a lack of good characterization of this change [4–7]. In addition to the above-mentioned factors, other ocular diseases like keratoconus and keratomalacia are also associated with the biomechanical properties of cornea [8,9]. Therefore, assessment of cornea elasticity is important for better understanding corneal pathologies, accurate diagnosing the related diseases, as well as improving the safety and efficacy of current refractive surgeries.
Surgical applications of intracorporal tissue adhesive agents: current evidence and future development
Published in Expert Review of Medical Devices, 2020
Nicholas Gillman, David Lloyd, Randy Bindra, Rui Ruan, Minghao Zheng
Resure® sealant (Ocular Therapeutix) is designed to prevent postoperative fluid egress from clear corneal incisions after intraocular lens placement in cataract surgery. The formulation contains a colorant to assist in visualization during application which diffuses onto bandages post-operatively, leaving a clear sealant which is removed in the tear film as epithelisation occurs [119]. The efficacy of the sealant shows that the use of Resure® sealant can significantly decrease adverse events compared to sutures [120]. The sealant has also been shown to decrease epithelial ingrowth following small incision lenticule extraction (SMILE) and laser-assisted in-situ keratomileusis (LASIK) procedures [121,122], reducing the risk of complications such as astigmatism and necrosis [123]. However, the sealant is unsuitable for ocular surgery requiring large incision sites, as it is only approved for incisions up to 3.5 mm in diameter. The curing time of Resure® sealant [124] can be affected by the use of hydrosoluble topical ophthalmic treatments, such as antibiotic, steroid, and analgesic.
EVO/EVO+ Visian Implantable Collamer Lenses for the correction of myopia and myopia with astigmatism
Published in Expert Review of Medical Devices, 2023
Elena Martínez-Plaza, Alberto López-de la Rosa, Alberto López-Miguel, Alfredo Holgueras, Miguel J. Maldonado
Finally, keratorefractive procedures, such as laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE), are also widely used for the correction of myopia and myopia with astigmatism. Several studies have demonstrated the safety, efficacy, and predictability of performing both keratorefractive procedures and ICL implantation [92–95]. In addition, studies assessing the visual performance of LASIK and SMILE in comparison with central hole ICL lenses have revealed the slight superiority of the intraocular procedure regarding postoperative visual outcomes [92–95].