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Evaluation and Management of Neurotoxicity in Occupational Illnesses
Published in Lucio G. Costa, Luigi Manzo, Occupatinal Neurotoxicology, 2020
Many industrial chemicals have been shown to cause peripheral neuropathy17 (Table 1), usually a polyneuropathy, in a decreasing order a sensory-motor, a pure sensory, a pure motor polyneuropathy. The clinical picture includes distal weakness and wasting, decrease or loss of tendon reflexes, paresthesias, sensory impairment for all modalities (glove-and-stocking anesthesia), but often with a predominant deficit either of superficial or of vibration and position senses. An autonomic involvement may also occur (mainly postural hypotension, lack of sweating and sexual dysfunctions). These disorders may develop either in acute intoxications, as in thallium, arsenic, and carbon monoxide poisoning, or after prolonged exposures to agents, such as lead and organic solvents. Although the manifestations are fairly consistent from one toxin to another, some specific characteristics are unique to individual agents. For example, lead induces a motor neuropathy primarily involving wrist extensors.12 A mild peripheral neuropathy associated with concomitant signs of central nervous system involvement often occurs in carbon disulfide intoxication;51 a similar association was reported in tri-ortho-cresyl phosphate (TOCP) outbreaks. Both motor and sensory disorders occur in neuropathies due to n-hexane, methyl n-butyl ketone and acrylamide, while sensory ataxia, sweating of palms and desquamation (hands and soles) are typical of acrylamide-induced neuropathy. Distal paresthesias and painful limbs are distinctive features of thallium and arsenic neuropathies, while an increased sensitivity to touch of feet and sensory involvement predominate in the relatively rare neuropathy due to alkyl mercury poisoning.1
GaitWear: a smartwatch application for in-the-wild gait normalisation based on a virtual field study assessing the effects of visual and haptic cueing
Published in Behaviour & Information Technology, 2021
Ana de Oliveira, Mohamed Khamis, Augusto Esteves
Examples of neurological disorders that tend to affect a person's gait include strokes, Parkinson's disease, myelopathy and sensory ataxia (Pirker and Katzenschlager 2017). These tend to produce different effects on gait, and as such, we motivate the gait normalisation approaches we explore later on the effects of Parkinson's' disease. This is considered the second most widespread neurodegenerative disorder after Alzheimer's disease, affecting over 10 million people worldwide (Parkinson 2002).
Neurological disease prediction using impaired gait analysis for foot position in cerebellar ataxia by ensemble approach
Published in Automatika, 2023
M. Shanmuga Sundari, Vijaya Chandra Jadala
Neurological conditions like sensory ataxia and CA have an important impact on the quality of life of patients; for this reason, early detection is crucial and essential. Wireless sensing without contact has been suggested in this research as a way to distinguish between the symptoms of the diseases. The benefits include increased comfort, reduced self-consciousness, and other things. The system's convenience and cost advantage are its key benefits.