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Potential of Microalgae for Protein Production
Published in Sanjeet Mehariya, Shashi Kant Bhatia, Obulisamy Parthiba Karthikeyan, Algal Biorefineries and the Circular Bioeconomy, 2022
Elena M. Rojo, Alejandro Filipigh, David Moldes, Marisol Vega, Silvia Bolado
Regarding antibacterial activities, the Kawaguchipeptin B peptide (extracted from Microcystis Aeruginosa) showed promising antibacterial activity results against Staphylococcus aureus (Ishida et al., 1997). The peptide Pahayokolides A (isolated from Lyngbya sp.) proved to target Bacillus Megaterium and Bacillus Subtilis effectively (Berry et al., 2004). Guzmán et al. (2019) identified antimicrobial peptides from Tetraselmis suecica, which acted against gram-positive and gram-negative bacteria. A bioactive peptide hydrolysate from Nannochloropsis oculate protein has shown an inhibitory effect on angiotensin-converting enzyme-I (ACE-I), a metalloprotease that catalyzes a dipeptide's cleavage and could be an effective antihypertensive treatment or used to manage cardiovascular diseases.
Nanoantibiotics
Published in Sourav Bhattacharjee, Principles of Nanomedicine, 2019
Oil-in-water (o/w) nanoemulsions with optical translucency and stability have emerged as capable antimicrobial agents [94, 95]. Such nanoemulsions from soybean oil have shown effect against Gm+ve (but not Gm–ve) bacteria [96, 97]. Microemulsion of Tween 80, pentanol, and ethyl oleate demonstrated bactericidal activity against Staphylococcus aureus, and both resistant and biofilm forming Pseudomonas aeruginosa [98, 99]. An aqueous nanoemulsion consisting of soybean oil, Triton X-100, and tri-n-butyl phosphate called BCTP caused membrane disruption in both bacteria and viruses while exhibiting a sporicidal effect against Bacillus cereus, Bacillus circulans, Bacillus megaterium, and Bacillussubtilis [100]. A mixture of BCTP and P10 liposomes called NB-401 was highly effective against microbes (Burkholderia, Pseudomonas, and Acinetobacter sp.), causing RTI in CF, or was able to grow in planktonic populations (Staphylococcus aureus, Pseudomonas aeruginosa, etc.). In vivo studies with inhaled preparations of NB-401 did not show any pulmonary inflammation or other pathology on postmortem examination, highlighting its biocompatibility. Inhaled o/w nanoemulsions as vaccines against hepatitis B and anthrax have also shown excellent efficacy and adequate safety profile in vivo [101].
Nanosized metal oxides (NMOs) and polyoxometalates (POMs) for antibacterial water treatment
Published in Alberto Figoli, Jan Hoinkis, Sacide Alsoy Altinkaya, Jochen Bundschuh, Application of Nanotechnology in Membranes for Water Treatment, 2017
Giulia Fiorani, Gloria Modugno, Marcella Bonchio, Mauro Carraro
CaO and MgO are low-cost, biocompatible and available materials which display antibacterial activity against both Gram-positive (e.g. Bacillus subtilis, Bacillus megaterium) and Gram-negative bacteria (e.g. E. coli) (Koper et al., 2002). Their surface activity is related to an alkalinity increase upon hydration and to the production of ROS (superoxide anion radical) (Yamamoto et al., 2010). In addition, MgO NPs can damage the cell membrane and cause the leakage of intracellular content (Leung et al., 2014).
Environmental sustainability in construction: Influence of Megaterium Bacteria on the durability and mechanical properties of concrete incorporating calcined clay
Published in Mechanics of Advanced Materials and Structures, 2023
Ashish Shukla, Nakul Gupta, Nanna Sri Ramya, Kuldeep K. Saxena, Amjad Iqbal, Faramarz Djavanroodi
Megaterium is a rod-shaped, Gram-positive, oxygenated microbe bacterium that may be found in a wide range of environments [45, 46]. Bacillus Megaterium is one of the largest microbes known, with cell lengths of up to 4 μm as well as a diameter of 1.5 μm. Bacillus Megaterium thrives in temp ranging from 3 °C − 45 °C, with the ideal temperature hovering around 30 °C. It was discovered that certain isolates from an Antarctic geothermal reservoir could thrive at temperatures as high as 63 °C. It’s a bacterium that may be found in the soil. This bacterium has the ability to precipitate CaCO3 whenever it comes into contact with concrete structure [47–49].