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Alkaloids potential health Benefits and toxicity
Published in Quan V. Vuong, Utilisation of Bioactive Compounds from Agricultural and Food Waste, 2017
Renée A. Street, Gerhard Prinsloo, Lyndy J. McGaw
Detection of toxic plant alkaloids in human and plant samples plays an imperative role in clinical and forensic toxicology investigation of suspected herbal poisoning cases (Beyer et al. 2009, Ng et al. 2013). Analytical methods of some toxic alkaloids in biological samples have been developed and described; however, most of these methods detect only one particular group of alkaloids. Commonly used methods include high performance liquid chromatography (HPLC), gas chromatography–mass spectrometry (GC–MS), capillary electrophoresis, liquid chromatography–mass spectrometry (LC– MS), and liquid chromatography–tandem mass spectrometry (LC–MS/MS) (Beyer et al. 2009, Ng et al. 2013). Ng et al. (2013) recently developed and validated a LC–MS/ MS method for simultaneous detection of 22 toxic plant alkaloids in herbal and urine samples. The alkaloids included aconitum alkaloids and their hydrolyzed products (aconitine, hypaconitine, mesaconitine, yunaconitine, crassicauline A, benzoylaconine, benzoylmesaconine, benzoylhypaconine, deacetylyunaconitine, deacetylcrassicauline A), solanaceous tropane alkaloids (atropine, anisodamine, scopolamine, anisodine), sophora alkaloids (matrine, sophoridine, oxymatrine, cytisine, N-methylcytisine), strychnos alkaloids (brucine, strychnine) and colchicine.
Antibacterial, cytotoxicity and biodegradability studies of polycaprolactone nanofibers holding green synthesized Ag nanoparticles using atropa belladonna extract
Published in Journal of Biomaterials Science, Polymer Edition, 2022
Muhammed Onur Avci, Nedim Muzoglu, Aysel Ersoy Yilmaz, Binboga Siddik Yarman
Atropa belladonna is a perennial herb belonging to the Solanaceae family and has a very intensive source of tropane alkaloids. This plant includes tropane alkaloids, atropine, hyoscyamine, scopolamine and anisodamine. Atropine is the important chemical of this plant and is mostly found in its leaves and black fruits. The leaves, fruits, stems and roots of this plant have been used in the treatment of many diseases such as joint pain, muscle spasms, brain, eye and acute inflammation, scarlatina, pancreatitis and neurological disorders [10,39]. In addition, atropa belladonna is included in over-the-counter medications that are not approved by the FDA for human use and it is used as a sedative to stop spasms such as cough, cold, asthma, whooping cough, bronchitis, Parkinson’s disease (PD), neuralgia, and rheumatism [40]. As a result of chemical studies, it has been revealed that these plants also have strong antioxidant and anti-cancer properties [41]. Considering the enormous medicinal significance of atropa belladonna, AgNPs have been produced by green synthesis using its extract and successful studies have been conducted on their therapeutic potential [10,42]. Many active ingredients are found in atropa belladonna play an important role as reducing and covering agents. The current study aims to reveal the antibacterial and cytotoxic properties of biodegradable PCL nanofibers doped with AgNPs biosynthesized using atropa belladonna extract, which has therapeutic potential.
The use of Brugmansia arborea as a green corrosion inhibitor for AISI 1018 carbon steel in acid media
Published in Green Chemistry Letters and Reviews, 2021
Adriana Rodríguez Torres, María Guadalupe Valladares Cisneros, Jorge Uruchurtu Chavarín, Cecilia Cuevas Arteaga, María Aurora Veloz Rodríguez
Brugmansia arborea is commonly known in Mexico as Floripondio, it is a native plant of South America and it belongs to the Solanaceae family (19). This family is known for producing alkaloids, tropane particularly, which is widely used in traditional medicine due to its anticholinergic properties (20). Figure 1 shows some of the chemical compounds that have been reported for B. arborea, which are: hyoscyamine (I), anisodamine (II) and scopolamine (III); this last compound is considered of great commercial value due to its pharmacological activity and minor side effects (21). Some heteroatoms such as N and O, as well as the presence of π-electrons in carbon–carbon double bonds in the chemical compounds of B. arborea, make it a potential corrosion inhibitor. Therefore, in the present work, extract of B. arborea with acetone, hexane and methanol was tested as corrosion inhibitor of 1018 steel in acid media.