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A Study of Mesh Implants Coated with a Biocompatible Polyhydroxyalkanoates Layer
Published in Tatiana G. Volova, Yuri S. Vinnik, Ekaterina I. Shishatskaya, Nadejda M. Markelova, Gennady E. Zaikov, Natural-Based Polymers for Biomedical Applications, 2017
Tatiana G. Volova, Yuri S. Vinnik, Ekaterina I. Shishatskaya, Nadejda M. Markelova, Gennady E. Zaikov
Achievement of better outcomes of surgical interventions in abdominal surgery is impossible without using new materials. For instance, surgical treatment of the patients with postoperative ventral hernias of the anterior abdominal wall has been one of the challenges in abdominal surgery. Hernia formation is a complex condition, caused by imbalance between intra-abdominal pressure and resistivity of the abdominal wall. Surgery using local tissues does not ensure stable improvement. The employment of tension-free techniques in surgeries of the postoperative ventral hernias and the use of synthetic materials was a revolution in hernia repair. Meshes can be implanted in super-aponeurotic, sub-aponeurotic, and intramuscular positions. However, plastic surgery of the anterior abdominal wall involving the use of synthetic allografts is a complicated surgical procedure and may cause the development of postoperative complications, both specific and nonspecific ones. Support meshes of a new generation are needed for hernia repair, which is one of the most common surgical operations, amounting to 10–15% of all surgeries. More than 20 million herniotomies are performed in the world, with recurrent hernias appearing in 10–15% (Fedorov and Adamyan, 2000). So-called barrier techniques are being developed to prevent surgical adhesions. Materials used to prepare such meshes should be able to prevent adhesions to internal organs, be resistant to infection, be mechanically strong, and tolerate long-term tension without deep scarring and encapsulation.
Design of Abdominal Wall Hernioplasty Meshes Guided by Mechanobiology and the Wound Healing Response
Published in Jiro Nagatomi, Eno Essien Ebong, Mechanobiology Handbook, 2018
Shawn J. Peniston, Karen J.L. Burg, Shalaby W. Shalaby
The most common wound to the abdominal wall is inguinal hernia, which is surgically repaired at the annual rate of 800,000 in the United States, 200,000 in Germany, 100,000 in France, 80,000 in the United Kingdom, and 12,000 in Finland [40–42]. Hernias of the abdominal wall form at areas that are susceptible to loss of mechanical integrity through acquired or congenital pathologies. The weak points of the abdominal wall are the inguinal, umbilical, and femoral canal regions. From epidemiology data, it is known that the prevalence rates for abdominal wall hernias are approximately 73% inguinal, 9.5% umbilical, 6.2% incisional, 2.7% femoral, and 8.6% other types such as spigelian, hiatal, or epigastric [43]. Inguinal hernias are classified as direct or indirect.
Gastrointestinal system
Published in David A Lisle, Imaging for Students, 2012
The term ‘hernia’ refers to abnormal protrusion of intra-abdominal contents, usually peritoneal fat and bowel loops. Inguinal hernia accounts for about 80 per cent of abdominal wall hernias. Femoral hernia is more common in females. Other types of external hernia include umbilical hernia and hernia related to previous surgery, either incisional or parastomal. Most hernias present with an inguinal or abdominal wall mass that increases in size when the patient stands or strains. Occasionally, hernias may become strangulated and present with localized pain and intestinal obstruction.
Combined numerical and experimental approach to determine numerical model of abdominal scaffold
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2022
Agnieszka Tomaszewska, Daniil Reznikov
Different solutions for ventral hernia management are discussed in the literature with the aim to find best ones in various medical cases (Baylón et al. 2017; Bittner et al. 2019). In the surgical intervention the hernia orifice is sewed or repaired with the use of mesh, which rebuilds abdominal wall in the orifice. The abdominal wall-implant system is therefore created. Mathematical modelling of the system helps to determine best medical solutions (Szymczak et al. 2017; Todros et al. 2017; He et al. 2020) and in a consequence to reduce hernia recurrence rate, which up to day is still very high, up to 25% in incisional hernia cases (Hoffmann et al. 2021). However, reliable data concerning geometry, boundary conditions, loading and constitutive model of the materials are required as an input for the numerical analysis.
Multiscale mechanical characterization of knitted abdominal wall repair meshes
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2020
Baptiste Pierrat, Nahime Al Abiad, Anicet Le Ruyet, Stéphane Avril
Abdominal wall hernia (AWH) is a protrusion of the abdominal cavity contents through a defect in the abdominal wall. AWH repair is one of the most common surgeries worldwide and the use of mesh has become standard of care. Despite tremendous progress in the treatment, complications remain with AWH repair and reported recurrence rates are still high (Andersen et al. 2009), and represent significant socio-economic burden.