Congenitally corrected transposition of the great arteries
Jana Popelová, Erwin Oechslin, Harald Kaemmerer, Martin G St John Sutton, Pavel Žáček in Congenital Heart Disease in Adults, 2008
It is indicated, because of conduction disorders and pre-excitation syndrome (see previous section), also in asymptomatic adult patients with CCTGA. In symptomatic patients, Holter ECG monitoring is performed repeatedly.
Prognostic value of myocardial injury-related findings on resting electrocardiography for cardiovascular risk in the asymptomatic general population: the 12-year follow-up report from the Ansan-Ansung cohort
Published in Annals of Medicine, 2020
Jinho Shin, Yonggu Lee, Jin-Kyu Park, Jeong-Hun Shin, Young-Hyo Lim, Heo Ran, Hyun-Jin Kim, Hwan-Cheol Park
Participants who had a prior history of CV diseases, including myocardial infarction (MI), non-MI CADs, congestive heart failure and haemorrhagic/ischaemic stroke, were excluded from the study. These CV diseases were identified through the interviews conducted during the baseline evaluations. Previous diagnoses made by physicians were used as the definitions of these CV diseases. Non-MI CADs were identified through a binary question for the presence of physician-diagnosed angina pectoris without MI. Participants with any angina-related symptoms were also excluded. Participants with pre-excitation syndrome (Minnesota code 6-4-1), left or right bundle branch block (Minnesota code 7-1-1 and 7-2-1, respectively) or tachycardia ≥120 bpm were also excluded because of the STAs accompanying these conditions.
Pharmacotherapeutic strategies for atrial fibrillation in pregnancy
Published in Expert Opinion on Pharmacotherapy, 2019
Georgios Georgiopoulos, Dimitrios Tsiachris, Athanasios Kordalis, Christos Kontogiannis, Michael Spartalis, Panagiota Pietri, Nikolaos Magkas, Christodoulos Stefanadis
Diagnostic work-up in pregnant women with new-onset AF should focus in the examination of possible underlying cardiac structural disorder, since this should be present in most cases. As in all AF patients, this arrythmia might be related to valvulopathy, hypertrophic cardiomyopathy, congenital heart disease, pre-excitation syndrome, thyroid disease, electrolyte imbalance, pharmacological effects, or alcohol abuse. Thus, besides electrocardiogram and physical examination, it would be helpful to perform some basic laboratory tests, that is echocardiogram, extended biochemical analyses and evaluation of thyroid function. Importantly, in cases of AF lasting longer than 48 h, transesophageal echocardiography could play a role in the evaluation of atrial thrombus existence in order to proceed to cardioversion [1,41]. Necessity for more specific tests, such as 24-h Holter monitoring or ischemia tests, depends on symptoms and concomitant heart disease (if present). Electrocardiogram should be reviewed by an experienced cardiologist or electrophysiologist for pre-excitation and Brugada syndrome. Presence of congenital heart disease or rheumatic valvular disease should always be evaluated with echocardiography by an experienced operator.
Etripamil nasal spray: an investigational agent for the rapid termination of paroxysmal supraventricular tachycardia (SVT)
Published in Expert Opinion on Investigational Drugs, 2020
Anthony H. Kashou, Peter A. Noseworthy
While etripamil nasal spray has the potential to alter acute management of SVT, it is important to remain cautious of the existing unknowns. A major concern involves unidentified adverse events (e.g. complete AV block, sinus pause, ventricular arrhythmias), especially in elderly patients, those on other anti-arrhythmic or AV nodal blocking medications (e.g. digoxin, beta-blockers, calcium-channel blocks), and those with undiagnosed pre-excitation syndrome. Prior to prescribing patients with a new medication to administer at home away from medical personnel, it will be crucial to ensure adverse events are clarified and that safety measures are in place for patients.
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